Dr. Ioannis Mantzaris, MD
Claim this profileMontefiore Medical Center - Moses Campus
Studies Acute Myelogenous Leukemia
Studies Acute Myeloid Leukemia
10 reported clinical trials
27 drugs studied
Area of expertise
1Acute Myelogenous Leukemia
RARA positive
t(9;22) translocation positive
FLT3 positive
2Acute Myeloid Leukemia
RARA positive
t(9;22) translocation positive
FLT3 positive
Affiliated Hospitals
Clinical Trials Ioannis Mantzaris, MD is currently running
Venetoclax + Chemotherapy
for Acute Myeloid Leukemia
This is a Phase 1b, open-label study evaluating Venetoclax in combination with intensive induction and consolidation chemotherapy in previously untreated, adult patients with acute myeloid leukemia. In Part 1, the dose escalation phase, the safety and tolerability of the combination with Venetoclax at different doses and duration will inform the appropriate dose(s) and regimen(s) for Part 2. In Part 2, the dose expansion phase, a maximum of 28 additional patients will be randomized 1:1 to the MTD determined in Part 1 and the starting dose (assuming the MTD is not the starting dose), to further evaluate the safety and efficacy of the study drug combination.
Recruiting1 award Phase 1
Blinatumomab + Chemotherapy
for Leukemia
This phase III trial compares the effect of usual treatment of chemotherapy and steroids and a tyrosine kinase inhibitor (TKI) to the same treatment plus blinatumomab. Blinatumomab is a Bi-specific T-Cell Engager ('BiTE') that may interfere with the ability of cancer cells to grow and spread. The information gained from this study may help researchers determine if combination therapy with steroids, TKIs, and blinatumomab work better than the standard of care.
Recruiting2 awards Phase 310 criteria
More about Ioannis Mantzaris, MD
Clinical Trial Related2 years of experience running clinical trials · Led 10 trials as a Principal Investigator · 5 Active Clinical TrialsTreatments Ioannis Mantzaris, MD has experience with
- Venetoclax
- Cytarabine
- Azacitidine
- Daunorubicin Hydrochloride
- Dexamethasone
- Decitabine And Cedazuridine
Breakdown of trials Ioannis Mantzaris, MD has run
Acute Myelogenous Leukemia
Acute Myeloid Leukemia
Myelodysplastic Syndrome
Myeloproliferative Disorder
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Ioannis Mantzaris, MD specialize in?
Ioannis Mantzaris, MD focuses on Acute Myelogenous Leukemia and Acute Myeloid Leukemia. In particular, much of their work with Acute Myelogenous Leukemia has involved RARA positive patients, or patients who are t(9;22) translocation positive.
Is Ioannis Mantzaris, MD currently recruiting for clinical trials?
Yes, Ioannis Mantzaris, MD is currently recruiting for 5 clinical trials in Bronx New York. If you're interested in participating, you should apply.
Are there any treatments that Ioannis Mantzaris, MD has studied deeply?
Yes, Ioannis Mantzaris, MD has studied treatments such as Venetoclax, Cytarabine, Azacitidine.
What is the best way to schedule an appointment with Ioannis Mantzaris, MD?
Apply for one of the trials that Ioannis Mantzaris, MD is conducting.
What is the office address of Ioannis Mantzaris, MD?
The office of Ioannis Mantzaris, MD is located at: Montefiore Medical Center - Moses Campus, Bronx, New York 10467 United States. This is the address for their practice at the Montefiore Medical Center - Moses Campus.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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