Dr. Hector Garcia-Chavez, MD
Claim this profileBaylor College of Medicine
Studies Crohn's Disease
Studies Colon Cancer
2 reported clinical trials
4 drugs studied
Area of expertise
1Crohn's Disease
2Colon Cancer
MSS negative
pMMR negative
MSS positive
Affiliated Hospitals
Clinical Trials Hector Garcia-Chavez, MD is currently running
Chemoimmunotherapy
for Colon Cancer
This is a Phase II open-label trial of neoadjuvant immunochemotherapy with Atezolizumab and CAPOX followed by surgery and potentially adjuvant chemotherapy for patients with localized resectable pMMR adenocarcinoma of the colon with a target accrual of 28 patients. The investigators will explore if appropriately timed neoadjuvant CAPOX with anti-PD-L1 mAb (Atezolizumab) can be administered safely and feasibly, and that this combination will lead to improved clinical response associated with enhanced numbers of immune cells in surgically resected colon tumors. Patients will receive 4 cycles of atezolizumab in combination with 4 cycles of CAPOX (atezolizumab will be administered prior to chemotherapy) before standard of care surgical resection. Following surgery, patients still considered to be at high-risk of recurrence (per SOC guidelines) will receive further adjuvant chemotherapy (mFOLFOX6 or CAPOX), based on the discretion of the treating oncologist/investigator. Circulating tumor DNA (ctDNA) dynamic change status will be analyzed through collection of blood samples throughout different stages of the patient's neoadjuvant treatment regimen (baseline, pre-neoadjuvant therapy, mid-neoadjuvant, post-neoadjuvant therapy, and during postoperative period) as a marker of early read on efficacy. The end of the study for each patient enrolled will be at the 6 month postoperative visit. On Study Protocol: Patients will be followed up for an efficacy follow-up phase during the first 6 months after surgery (week 2 \& months 3, 6 visits). All assessments beyond the 6 month visit will be performed under standard of care surveillance office visits. Off Study Protocol: Thereafter they will enter a survival follow-up phase per standard of care protocols. Patients will be seen every 6 months starting at month 12 until month 36. All collection of research-specific assessments including whole blood, stool collection and quality of life questionnaires will be optional beyond the 6 month postop visit (months 12-36).
Recruiting1 award Phase 2
Kono-S vs Side-to-Side Anastomosis
for Crohn's Disease
This study proposes a randomized prospective study comparing the Kono-S anastomosis to the standard side-to-side anastomosis.This will be a multi-center randomized prospective trial. Patients with Crohn's ileitis or Crohn's ileocolitis requiring resection will be randomized to undergo either the Kono-S anastomosis or the side-to-side functional end anastomosis.
Recruiting1 award N/A2 criteria
More about Hector Garcia-Chavez, MD
Clinical Trial Related1 year of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Hector Garcia-Chavez, MD has experience with
- Kono-S Analstomosis
- Side-to-side Functional End Anastomosis
- Atezolizumab
- Capecitabine, Oxaliplatin
Breakdown of trials Hector Garcia-Chavez, MD has run
Crohn's Disease
Colon Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Hector Garcia-Chavez, MD specialize in?
Hector Garcia-Chavez, MD focuses on Crohn's Disease and Colon Cancer. In particular, much of their work with Crohn's Disease has involved treating patients, or patients who are undergoing treatment.
Is Hector Garcia-Chavez, MD currently recruiting for clinical trials?
Yes, Hector Garcia-Chavez, MD is currently recruiting for 2 clinical trials in Houston Texas. If you're interested in participating, you should apply.
Are there any treatments that Hector Garcia-Chavez, MD has studied deeply?
Yes, Hector Garcia-Chavez, MD has studied treatments such as Kono-S analstomosis, side-to-side functional end anastomosis, Atezolizumab.
What is the best way to schedule an appointment with Hector Garcia-Chavez, MD?
Apply for one of the trials that Hector Garcia-Chavez, MD is conducting.
What is the office address of Hector Garcia-Chavez, MD?
The office of Hector Garcia-Chavez, MD is located at: Baylor College of Medicine, Houston, Texas 77030 United States. This is the address for their practice at the Baylor College of Medicine.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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