Dr. Gregory A. Masters

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Helen F Graham Cancer Center

Expert in Breast Cancer
Expert in Breast cancer
133 reported clinical trials
213 drugs studied

About Gregory A. Masters

Education:

  • Obtained an MD from Jefferson Medical College, Philadelphia, PA, in 1985.

Experience:

  • Board Certified in Internal Medicine and Medical Oncology.
  • Serves as a Clinical Professor of Medicine at Thomas Jefferson University.
  • Director of the Lung Cancer Program at the Helen F. Graham Cancer Center & Research Institute.
  • Founding member and past president of the International Association for the Study of Lung Cancer (IASLC).
  • Held the position of President of the American Society of Clinical Oncology (ASCO) in 2016.

Area of expertise

1Breast Cancer
Global Leader
Gregory A. Masters has run 27 trials for Breast Cancer. Some of their research focus areas include:
HER2 positive
Stage II
ER positive
2Breast Cancer
Global Leader
Gregory A. Masters has run 22 trials for Breast cancer. Some of their research focus areas include:
HER2 positive
Stage II
Stage I

Affiliated Hospitals

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Helen F. Graham Cancer Center
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Beebe South Coastal Health Campus

Clinical Trials Gregory A. Masters is currently running

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Chemotherapy + Immunotherapy

for Esophageal and Gastric Cancer

This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.
Recruiting2 awards Phase 32 criteria
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Chemotherapy + Hormone Therapy

for Breast Cancer

This trial is testing if adding additional cancer-fighting drugs to treatments that stop certain body functions is better than just using the treatments that stop those functions alone. It targets younger women with early-stage breast cancer who have a higher risk of dying from the disease. The treatment works by stopping certain body functions and using drugs to kill cancer cells.
Recruiting2 awards Phase 319 criteria

More about Gregory A. Masters

Clinical Trial Related6 years of experience running clinical trials · Led 133 trials as a Principal Investigator · 50 Active Clinical Trials
Treatments Gregory A. Masters has experience with
  • Carboplatin
  • Nivolumab
  • Paclitaxel
  • Pembrolizumab
  • Atezolizumab
  • Cisplatin

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