Dr. Frances Valdes-Albini, MD
Claim this profileUniversity of Miami
Studies Breast Cancer
Studies Breast cancer
6 reported clinical trials
20 drugs studied
Area of expertise
1Breast Cancer
HER2 positive
ER positive
Stage IV
2Breast Cancer
HER2 positive
ER positive
ER negative
Affiliated Hospitals
Clinical Trials Frances Valdes-Albini, MD is currently running
Chemotherapy + Hormone Therapy
for Breast Cancer
This trial is testing if adding additional cancer-fighting drugs to treatments that stop certain body functions is better than just using the treatments that stop those functions alone. It targets younger women with early-stage breast cancer who have a higher risk of dying from the disease. The treatment works by stopping certain body functions and using drugs to kill cancer cells.
Recruiting2 awards Phase 319 criteria
Early Treatment Switch Strategies
for Advanced Breast Cancer
The majority of patients (pts) with breast cancer have hormone receptor positive (HR+) disease, and this holds true for pts with advanced breast cancer (ABC). Currently frontline therapy for pts with HR+ ABC is antihormonal therapy with an aromatase inhibitor or selective estrogen receptor degrader plus a CDK4/6i. The proposed trial is a randomized study to further evaluate the potential benefit of switching a frontline regimen at the time that a molecular signal, ctDNA, suggests progression prior to detection of clinical progression using standard methods. The purpose of this study is to determine whether switching treatment earlier in the disease process, based on molecular progression, will increase the amount of time that a patient's metastatic breast cancer is controlled compared to patients with metastatic breast cancer who receive treatment later based on diagnostic imaging results or other methods currently used in medical practice.
Recruiting1 award Phase 213 criteria
More about Frances Valdes-Albini, MD
Clinical Trial Related1 year of experience running clinical trials · Led 6 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Frances Valdes-Albini, MD has experience with
- Tucatinib
- AI+CDK4/6i
- Chemotherapy
- MTOR Inhibitor + AI
- MTOR Inhibitor + Selective Estrogen Receptor Modulator
- MTOR Inhibitor + SERD
Breakdown of trials Frances Valdes-Albini, MD has run
Breast Cancer
Breast cancer
Relapse
Solid Tumors
Esophageal Cancer
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