Erica Mayer, MD, MPH - Dana-Farber

Dr. Erica L. Mayer, MD MPH

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Dana-Farber Cancer Institute

Studies Breast Cancer
Studies BRCA1 Mutation
8 reported clinical trials
19 drugs studied

Area of expertise

1Breast Cancer
Erica L. Mayer, MD MPH has run 8 trials for Breast Cancer. Some of their research focus areas include:
Stage II
HER2 negative
Stage III
2BRCA1 Mutation
Erica L. Mayer, MD MPH has run 1 trial for BRCA1 Mutation. Some of their research focus areas include:
HER2 negative
ER positive
ER negative

Affiliated Hospitals

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Dana Farber Cancer Institute
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Dana Farber Cancer Institute (Data Collection Only)

Clinical Trials Erica L. Mayer, MD MPH is currently running

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Enzalutamide + Mifepristone or Chemotherapy

for Breast Cancer

The researchers are doing this study to find out if the study drug, enzalutamide, alone or combined with the study drug, mifepristone, is effective in treating advanced or metastatic androgen receptor-positive (AR+) triple negative breast cancer (TNBC) or estrogen receptor-low breast cancer (ER-low BC), and whether these study treatments work as well as standard chemotherapy with carboplatin, paclitaxel, capecitabine, or eribulin.
Recruiting1 award Phase 218 criteria
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Avelumab Combinations

for Triple Negative Breast Cancer

This phase II trial studies how well the combination of avelumab with liposomal doxorubicin with or without binimetinib, or the combination of avelumab with sacituzumab govitecan works in treating patients with triple negative breast cancer that is stage IV or is not able to be removed by surgery (unresectable) and has come back (recurrent). Immunotherapy with checkpoint inhibitors like avelumab require activation of the patient's immune system. This trial includes a two week induction or lead-in of medications that can stimulate the immune system. It is our hope that this induction will improve the response to immunotherapy with avelumab. One treatment, sacituzumab Govitecan, is a monoclonal antibody called sacituzumab linked to a chemotherapy drug called SN-38. Sacituzumab govitecan is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of tumor cells, known as Tumor-associated calcium signal transducer 2 (TROP2) receptors, and delivers SN-38 to kill them. Another treatment, liposomal doxorubicin, is a form of the anticancer drug doxorubicin that is contained in very tiny, fat-like particles. It may have fewer side effects and work better than doxorubicin, and may enhance factors associated with immune response. The third medication is called binimetinib, which may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth, and may help activate the immune system. It is not yet known whether giving avelumab in combination with liposomal doxorubicin with or without binimetinib, or the combination of avelumab with sacituzumab govitecan will work better in treating patients with triple negative breast cancer.
Recruiting1 award Phase 211 criteria

More about Erica L. Mayer, MD MPH

Clinical Trial Related4 years of experience running clinical trials · Led 8 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Erica L. Mayer, MD MPH has experience with
  • Palbociclib
  • Avelumab
  • Exemestane
  • Standard Adjuvant Endocrine Therapy
  • Abemaciclib
  • Anastrozole/Letrozole

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