Dr. Dennis F. Moore

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Ascension Via Christi Hospitals Wichita

Studies Lung Cancer
Studies Breast Cancer
30 reported clinical trials
80 drugs studied

Area of expertise

1Lung Cancer
Dennis F. Moore has run 7 trials for Lung Cancer. Some of their research focus areas include:
Stage IV
Stage II
Stage III
2Breast Cancer
Dennis F. Moore has run 7 trials for Breast Cancer. Some of their research focus areas include:
HER2 positive
Stage II
Stage I

Affiliated Hospitals

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Ascension Via Christi Hospitals Wichita
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Cancer Center Of Kansas-Wichita Medical Arts Tower

Clinical Trials Dennis F. Moore is currently running

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Osimertinib + Bevacizumab

for Lung Cancer

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.
Recruiting2 awards Phase 331 criteria
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Lomustine + Standard Therapy

for Glioblastoma

This phase III trial compares the effect of adding lomustine to standard chemotherapy with temozolomide and radiation therapy versus temozolomide and radiation therapy alone in shrinking or stabilizing newly diagnosed MGMT methylated glioblastoma. MGMT methylated tumors are more likely to respond to temozolomide chemotherapy. Temozolomide is in a class of medications called alkylating agents. It works by damaging the cell's DNA and may kill tumor cells and slow down or stop tumor growth. Lomustine is a chemotherapy drug and in a class of medications called alkylating agents. It damages the cell's DNA and may kill tumor cells. Radiation therapy uses high energy x-ray photons to kill tumor cells and shrink tumors. Adding lomustine to standard chemotherapy with temozolomide and radiation therapy may shrink or stabilize glioblastoma.
Recruiting2 awards Phase 34 criteria

More about Dennis F. Moore

Clinical Trial Related4 years of experience running clinical trials · Led 30 trials as a Principal Investigator · 15 Active Clinical Trials
Treatments Dennis F. Moore has experience with
  • Radiation Therapy
  • Atezolizumab
  • Pembrolizumab
  • Carboplatin
  • Stereotactic Body Radiation Therapy
  • Biospecimen Collection

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