Dr. Debora S. Bruno
Claim this profileCase Western Reserve University
Area of expertise
Lung Cancer
Debora S. Bruno has run 7 trials for Lung Cancer. Some of their research focus areas include:
Non-Small Cell Lung Cancer
Debora S. Bruno has run 5 trials for Non-Small Cell Lung Cancer. Some of their research focus areas include:
Affiliated Hospitals
Case Western Reserve University
University Hospitals Cleveland Medical Center
Clinical Trials Debora S. Bruno is currently running
Osimertinib + Bevacizumab
for Lung Cancer
This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.
Recruiting
2 awards
Phase 3
31 criteria
Educational Intervention
for Disparities in Clinical Trial Access
This study focuses on psychosocial barriers at the patient level with the goal of promoting high quality decision making around clinical trials participation. The proposed study adapts the PRE-ACT model to racial and ethnic minority patients who were underrepresented in the original PRE-ACT study and will be combined with a patient navigator model.
Recruiting
1 award
N/A
More about Debora S. Bruno
Clinical Trial Related
5 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 4 Active Clinical Trials
Treatments Debora S. Bruno has experience with
- Nivolumab
- Bevacizumab
- Pembrolizumab
- Osimertinib
- Pemetrexed
- Educational Intervention
Breakdown of trials Debora S. Bruno has run
Lung Cancer
Non-Small Cell Lung Cancer
Educational Intervention
Solid Tumors
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Debora S. Bruno specialize in?
Debora S. Bruno focuses on Lung Cancer and Non-Small Cell Lung Cancer. In particular, much of their work with Lung Cancer has involved Stage IV patients, or patients who are Stage III.
Is Debora S. Bruno currently recruiting for clinical trials?
Yes, Debora S. Bruno is currently recruiting for 4 clinical trials in Cleveland Ohio. If you're interested in participating, you should apply.
Are there any treatments that Debora S. Bruno has studied deeply?
Yes, Debora S. Bruno has studied treatments such as Nivolumab, Bevacizumab, Pembrolizumab.
What is the best way to schedule an appointment with Debora S. Bruno?
Apply for one of the trials that Debora S. Bruno is conducting.
What is the office address of Debora S. Bruno?
The office of Debora S. Bruno is located at: Case Western Reserve University, Cleveland, Ohio 44106 United States. This is the address for their practice at the Case Western Reserve University.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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