Darin Dougherty, MD, MSc

Dr. Darin Dougherty, MD

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Massachusetts General Hospital

Studies Obsessive-Compulsive Disorder
Studies Depression
8 reported clinical trials
9 drugs studied

Affiliated Hospitals

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Massachusetts General Hospital
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Massachussetts General Hospital

Clinical Trials Darin Dougherty, MD is currently running

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Focused Ultrasound

for Anxiety

There are few treatment options available for patients once they have failed standard psychopharmacological therapy for generalized anxiety disorder. Existing brain stimulation methods such as rTMS fail to target deep brain structures associated with anxiety disorders; structures such as the amygdala. In this double-blind sham-controlled clinical trial, the investigators propose to establish baseline severity of anxiety in 48 patients, then deliver eight treatments over four sessions of focused ultrasound stimulation to the amygdala. Anxiety severity will be assessed using standard psychometric scales after each session, and at follow-ups.
Recruiting0 awards N/A6 criteria
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Deep Brain Stimulation

for Neurological and Psychiatric Conditions

We propose to study approach/avoidance behavior as measured by the Approach Avoidance task in 20 epilepsy patients undergoing implementation of depth electrodes for seizure monitoring in the Epilepsy Monitoring Unit at MGH. We will also study the effects of VC/VS electrical stimulation on approach-avoidance conflict in 20 adult patients who have undergone DBS implantation for severe MDD and/or OCD. There are 100-200 patients in the world with DBS electrodes in the VC/VS, and our research team cares for more than any other institution. Both participant groups will be assessed with respect to reward-aversion decision conflict using the task. The task will be performed with concurrent EEG recordings in DBS patients, and with continuous recording through our invasive neurophysiology rig in EMU subjects.
Recruiting1 award N/A2 criteria

More about Darin Dougherty, MD

Clinical Trial Related4 years of experience running clinical trials · Led 8 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Darin Dougherty, MD has experience with
  • Deep Brain Stimulation
  • Medtronic PC+S Deep Brain Stimulation
  • Medtronic Percept Deep Brain Stimulation
  • Deep Brain Stimulator
  • ON/OFF Stimulation And Reward Motivation
  • BrainSonix Pulsar 1002

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