Dr. Charles H. Redfern
Claim this profileSharp Memorial Hospital
Studies Cancer
Studies Brain Tumor
12 reported clinical trials
43 drugs studied
Area of expertise
1Cancer
Stage IV
HER2 positive
Stage III
2Brain Tumor
Stage IV
BRAF positive
NTRK positive
Affiliated Hospitals
Clinical Trials Charles H. Redfern is currently running
Targeted Therapy
for Brain Cancer
This phase II trial studies how well genetic testing works in guiding treatment for patients with solid tumors that have spread to the brain. Several genes have been found to be altered or mutated in brain metastases such as NTRK, ROS1, CDK, PI3K, or KRAS G12C. Medications that target these genes such as abemaciclib, paxalisib, entrectinib and adagrasib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Genetic testing may help doctors tailor treatment for each mutation.
Recruiting1 award Phase 217 criteria
DF1001
for Solid Cancers
This trial is testing a new treatment called DF1001-001 that helps the immune system target and destroy cancer cells. It focuses on patients with certain types of cancers that have a protein called HER2. The treatment works by activating immune cells to recognize and attack these cancer cells.
Recruiting1 award Phase 1 & 252 criteria
More about Charles H. Redfern
Clinical Trial Related8 years of experience running clinical trials · Led 12 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Charles H. Redfern has experience with
- Nivolumab
- Ipilimumab
- Xcellerated T CellsTM
- Pritumumab
- LHRH Analogue
- Abiraterone Acetate
Breakdown of trials Charles H. Redfern has run
Cancer
Brain Tumor
Prostate Cancer
Solid Tumors
Parotid Gland Cancer
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