Dr. Carmen Isache, MD
Claim this profileUniversity of Florida-JAX-ASCENT
Studies COVID-19
Studies Coronavirus
6 reported clinical trials
12 drugs studied
Area of expertise
1COVID-19
SARS-CoV-2
2Coronavirus
SARS-CoV-2
PCR
collection
Affiliated Hospitals
Clinical Trials Carmen Isache, MD is currently running
Sleep Treatments
for Long COVID Syndrome
The platform protocol is designed to be flexible so that it is suitable for a range of study settings and intervention types. Therefore, the platform protocol provides a general protocol structure that can be shared by multiple interventions and allows comparative analysis across the interventions. For example, objectives, measures, and endpoints are generalized in the platform protocol, but intervention-specific features are detailed in separate appendices. This platform protocol is a prospective, multi-center, multi-arm, randomized controlled platform trial evaluating potential interventions for PASC-mediated sleep disturbances. The hypothesis is that symptoms of sleep and circadian disorders that emerge in patients with PASC can be improved by phenotype-targeted interventions. Specific sleep and circadian disorders addressed in this protocol include sleep-related daytime impairment (referred to as hypersomnia) and complex PASC-related sleep disturbance (reflecting symptoms of insomnia and sleep-wake rhythm disturbance).
Recruiting0 awards Phase 21 criteria
Rehabilitation and Pacing
for Long COVID
This is a platform protocol designed to be flexible so that it is suitable for a range of interventions and settings within diverse health care systems and community settings with incorporation into clinical COVID-19 management programs and treatment plans if results achieve key study outcomes. This protocol is a prospective, multi-center, multi-arm, randomized, controlled platform trial evaluating interventions to address and improve exercise intolerance and post-exertional malaise (PEM) as manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC). The focus of this protocol is to assess interventions that can improve exercise capacity, daily activities tolerance, and quality of life in patients with PASC.
Recruiting1 award N/A2 criteria
More about Carmen Isache, MD
Clinical Trial Related1 year of experience running clinical trials · Led 6 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Carmen Isache, MD has experience with
- Placebo
- Montelukast
- Fluticasone
- Fluvoxamine
- Ivermectin
- Metformin
Breakdown of trials Carmen Isache, MD has run
COVID-19
Coronavirus
Post-COVID Syndrome
Long COVID Syndrome
Non-Rapid Eye Movement Parasomnia
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