Dr. Brea Lipe, MD
Claim this profileUniversity of Rochester
Studies Multiple Myeloma
Studies Relapse
9 reported clinical trials
17 drugs studied
Area of expertise
1Multiple Myeloma
Stage IV
HLA-A positive
2Relapse
HLA-A positive
Affiliated Hospitals
Clinical Trials Brea Lipe, MD is currently running
Curcumin + Piperine
for Prostate Cancer
This trial is testing if taking curcumin and piperine supplements can help prevent or slow down the progression of early-stage prostate cancer and certain blood conditions. The study will monitor a specific blood test to see if the disease is improving or getting worse. Curcumin, derived from the golden spice turmeric, has poor absorption in the body which can be improved when combined with piperine, a compound found in black pepper.
Recruiting1 award Phase 26 criteria
Combination Therapies with Selinexor
for Multiple Myeloma
This study will independently assess the efficacy and safety of 11 combination therapies in 12 arms, in dose-escalation/-evaluation and expansion phases, for the treatment of patients with relapsed/refractory multiple myeloma (RRMM) and newly diagnosed multiple myeloma (NDMM). The combinations to be evaluated are: * Arm 1: Selinexor + dexamethasone + pomalidomide (SPd); enrollment complete * Arm 2: Selinexor + dexamethasone + bortezomib (SVd); enrollment complete * Arm 3: Selinexor + dexamethasone + lenalidomide (SRd) in RRMM; enrollment complete * Arm 4: Selinexor + dexamethasone + pomalidomide + bortezomib (SPVd); enrollment complete * Arm 5: Selinexor + dexamethasone + daratumumab (SDd); enrollment complete * Arm 6: Selinexor + dexamethasone + carfilzomib (SKd); enrollment complete * Arm 7: Selinexor + dexamethasone + lenalidomide (SRd) in NDMM; enrollment complete * Arm 8: Selinexor + dexamethasone + ixazomib (SNd); enrollment complete * Arm 9: Selinexor + dexamethasone + pomalidomide + elotuzumab (SPEd); enrollment complete * Arm 10: Selinexor + dexamethasone + belantamab mafodotin (SBd); enrollment complete * Arm 11: Selinexor + dexamethasone + pomalidomide + daratumumab (SDPd); enrollment complete * Arm 12: Selinexor + dexamethasone + mezigdomide (SMd); actively recruiting Selinexor pharmacokinetics: * PK Run-in (Days 1-14): Starting in protocol version 8.0, patients enrolled to any arm in the Dose Escalation Phase (i.e., Arm 4 \[SPVd\], Arm 6 \[SKd\], Arm 8 \[SNd\], Arm 9 \[SPEd\], Arm 10 \[SBd\], and Arm 11 \[SDPd\]) will also first be enrolled to a pharmacokinetics (PK) Run-in period until 9 patients have been enrolled to this period to evaluate the PK of selinexor before and after co-administration with a strong CYP3A4 inhibitor. This run-in period does not apply to Arm 12 (SMd).
Recruiting1 award Phase 1 & 222 criteria
More about Brea Lipe, MD
Clinical Trial Related6 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Brea Lipe, MD has experience with
- Dexamethasone
- Daratumumab
- Bortezomib
- Carfilzomib
- Lenalidomide
- Pomalidomide
Breakdown of trials Brea Lipe, MD has run
Multiple Myeloma
Relapse
Prostate Cancer
Monoclonal Gammopathy
Bone Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Brea Lipe, MD specialize in?
Brea Lipe, MD focuses on Multiple Myeloma and Relapse. In particular, much of their work with Multiple Myeloma has involved Stage IV patients, or patients who are HLA-A positive.
Is Brea Lipe, MD currently recruiting for clinical trials?
Yes, Brea Lipe, MD is currently recruiting for 2 clinical trials in Rochester New York. If you're interested in participating, you should apply.
Are there any treatments that Brea Lipe, MD has studied deeply?
Yes, Brea Lipe, MD has studied treatments such as Dexamethasone, Daratumumab, Bortezomib.
What is the best way to schedule an appointment with Brea Lipe, MD?
Apply for one of the trials that Brea Lipe, MD is conducting.
What is the office address of Brea Lipe, MD?
The office of Brea Lipe, MD is located at: University of Rochester, Rochester, New York 14642 United States. This is the address for their practice at the University of Rochester.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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