Dr. Binod Dhakal, MD
Claim this profileMedical College of Wisconsin
Area of expertise
Multiple Myeloma
Binod Dhakal, MD has run 17 trials for Multiple Myeloma. Some of their research focus areas include:
Relapse
Binod Dhakal, MD has run 4 trials for Relapse. Some of their research focus areas include:
Affiliated Hospitals
Medical College Of Wisconsin
Froedtert Hospital & The Medical College Of Wisconsin
Clinical Trials Binod Dhakal, MD is currently running
Iberdomide Combo
for Multiple Myeloma
Similar to the paradigm established in other hematologic malignancies that are considered curable, the achievement of MRD(-) status is necessary for long term disease control in MM. The fact that the majority of patients remain MRD (+) after induction therapy and AHCT points to the opportunity to deploy novel agents with complementary mechanism of action and favorable toxicity profile to reach and maintain MRD (-) status. Given its favorable toxicity profile, the convenience of oral administration, and compelling single agent activity even in heavily pretreated MM, iberdomide is likely amenable to long term therapy in patients with high-risk of relapse/progression identified by the persistence of MRD(+). The investigators intend to develop combination(s) of iberdomide with other agents with complementary mechanism of action in the consolidation setting post AHCT in order to achieve and sustain MRD (-).
Recruiting
3 awards
Phase 1 & 2
14 criteria
Sequential Therapy
for Multiple Myeloma
This research study will determine the proportion of patients with lowest minimal residual disease (MRD) response obtainable after receiving 6 cycles of study treatment. Minimal residual disease is multiple myeloma cells below the level of 1 cancer cell out of 100,000 in the bone marrow. For patients who become MRD "negative" (i.e. less than 1 cancer cell out of 100,000) at the end of 6 cycles of therapy, this study will study if that good response can be maintained with 3 additional cycles of treatment instead of use of autologous hematopoietic cell transplantation (AHCT). For patients who are MRD "positive" at the end of 6 cycles of therapy, this study will answer whether more patients can become and remain MRD "negative" with AHCT plus teclistamab in combination with daratumumab when compared with patients who undergo AHCT followed by lenalidomide (an established anti-myeloma drug) plus daratumumab.
Recruiting
1 award
Phase 2
10 criteria
More about Binod Dhakal, MD
Clinical Trial Related
5 years of experience running clinical trials · Led 17 trials as a Principal Investigator · 5 Active Clinical Trials
Treatments Binod Dhakal, MD has experience with
- Dexamethasone
- Bortezomib
- Lenalidomide
- Daratumumab
- Isatuximab
- Pomalidomide
Breakdown of trials Binod Dhakal, MD has run
Multiple Myeloma
Plasma Cell Neoplasm
Renal Disease
Childhood Blood Disease
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Binod Dhakal, MD specialize in?
Binod Dhakal, MD focuses on Multiple Myeloma and Relapse. In particular, much of their work with Multiple Myeloma has involved Serum M-protein (SPEP) patients, or patients who are Urine M-protein (UPEP).
Is Binod Dhakal, MD currently recruiting for clinical trials?
Yes, Binod Dhakal, MD is currently recruiting for 5 clinical trials in Milwaukee Wisconsin. If you're interested in participating, you should apply.
Are there any treatments that Binod Dhakal, MD has studied deeply?
Yes, Binod Dhakal, MD has studied treatments such as Dexamethasone, Bortezomib, Lenalidomide.
What is the best way to schedule an appointment with Binod Dhakal, MD?
Apply for one of the trials that Binod Dhakal, MD is conducting.
What is the office address of Binod Dhakal, MD?
The office of Binod Dhakal, MD is located at: Medical College of Wisconsin, Milwaukee, Wisconsin 53226 United States. This is the address for their practice at the Medical College of Wisconsin.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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