Dr. Bhuvana Setty, M.D.
Claim this profileNationwide Children's Hospital
Area of expertise
Soft Tissue Sarcoma
Bhuvana Setty, M.D. has run 5 trials for Soft Tissue Sarcoma. Some of their research focus areas include:
Ewing Sarcoma
Bhuvana Setty, M.D. has run 4 trials for Ewing Sarcoma. Some of their research focus areas include:
Affiliated Hospitals
Nationwide Children's Hospital
The Research Institute At Nationwide Children's Hospital
Clinical Trials Bhuvana Setty, M.D. is currently running
NK Cells + Chemotherapy
for Sarcoma
The purpose of this study is to determine if the addition of infusions of a type of immune cell called a "natural killer", or NK cell to the sarcoma chemotherapy regimen GEM/DOX (gemcitabine and docetaxel) can improve outcomes in people with childhood sarcomas that have relapsed or not responded to prior therapies. The goals of this study are: * To determine the safety and efficacy of the addition of adoptive transfer of universal donor, TGFβ imprinted (TGFβi), expanded NK cells to the pediatric sarcoma salvage chemotherapeutic regimen gemcitabine/docetaxel (GEM/DOX) for treatment of relapsed and refractory pediatric sarcomas To determine the 6-month progression free survival achieved with this treatment in patients within cohorts of relapsed or refractory osteosarcoma, Ewing sarcoma, rhabdomyosarcoma and non-rhabdomyosarcoma soft tissue sarcoma. * To identify toxicities related to treatment with GEM/DOX + TGFβi expanded NK cells Participants will receive study drugs that include chemotherapy and NK cells in cycles; each cycle is 21 days long and you can receive up to 8 cycles. * Gemcitabine (GEM): via IV on Days 1 and 8 * Docetaxel (DOX): via IV on Day 8 * Prophylactic dexamethasone: Day 7-9 to prevent fluid retention and hypersensitivity reaction * Peg-filgrastim (PEG-GCSF) or biosimilar: Day 9 to help your white blood cell recover and allow more chemotherapy to be given * TGFβi NK cells: via IV on Day 12
Recruiting
1 award
Phase 1 & 2
Liquid Biopsy
for Bone Cancer
This trial is testing a blood test that looks for small pieces of tumor DNA in patients with Ewing sarcoma or osteosarcoma. The goal is to see if this test can help predict if the cancer will return after treatment. A group of patients will participate to help researchers understand how useful this test can be.
Recruiting
1 award
N/A
15 criteria
More about Bhuvana Setty, M.D.
Clinical Trial Related
4 years of experience running clinical trials · Led 10 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Bhuvana Setty, M.D. has experience with
- Gemcitabine
- Cyclophosphamide
- Vincristine
- Docetaxel
- TGFβi Expanded NK Cells
- Vinorelbine
Breakdown of trials Bhuvana Setty, M.D. has run
Soft Tissue Sarcoma
Ewing Sarcoma
Bone Cancer
Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Bhuvana Setty, M.D. specialize in?
Bhuvana Setty, M.D. focuses on Soft Tissue Sarcoma and Ewing Sarcoma. In particular, much of their work with Soft Tissue Sarcoma has involved Stage IV patients, or patients who are PAX/FOXO1 fusion positive.
Is Bhuvana Setty, M.D. currently recruiting for clinical trials?
Yes, Bhuvana Setty, M.D. is currently recruiting for 2 clinical trials in Columbus Ohio. If you're interested in participating, you should apply.
Are there any treatments that Bhuvana Setty, M.D. has studied deeply?
Yes, Bhuvana Setty, M.D. has studied treatments such as Gemcitabine, Cyclophosphamide, Vincristine.
What is the best way to schedule an appointment with Bhuvana Setty, M.D.?
Apply for one of the trials that Bhuvana Setty, M.D. is conducting.
What is the office address of Bhuvana Setty, M.D.?
The office of Bhuvana Setty, M.D. is located at: Nationwide Children's Hospital, Columbus, Ohio 43205 United States. This is the address for their practice at the Nationwide Children's Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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