Dr. Arthur Winer, MD

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Inova Schar Cancer Institute

Studies Liver Cancer
Studies Bile Duct Cancer
4 reported clinical trials
10 drugs studied

Affiliated Hospitals

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Inova Schar Cancer Institute

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Inova Fairfax Hospital

Clinical Trials Arthur Winer, MD is currently running

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Memantine

for Liver Cancer

This is a single-site prospective study to describe efficacy endpoints of single agent memantine in patients with unresectable, locally advanced, or metastatic HCC otherwise not deemed candidates for intensive systemic therapy. In addition to the primary endpoint and multiple secondary efficacy endpoints, we will describe changes in quality of life on treatment over time.

Recruiting

1 award

Phase 2 & 3

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Chemotherapy + Immunotherapy

for Esophageal and Gastric Cancer

This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.

Recruiting

2 awards

Phase 3

2 criteria

More about Arthur Winer, MD

Clinical Trial Related

2 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 3 Active Clinical Trials

Treatments Arthur Winer, MD has experience with

  • Gemcitabine
  • Nab-paclitaxel
  • Cisplatin
  • Yittrium-90
  • Memantine
  • Fluorouracil

Breakdown of trials Arthur Winer, MD has run

Hepatocellular Carcinoma

Fibrosing Colonopathy

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