Dr. Antony Ruggeri - Regenerative ...

Dr. Antony Ruggeri

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Aurora Cancer Care-Milwaukee West

Studies Pancreatic Cancer
Studies Colon Cancer
14 reported clinical trials
57 drugs studied

Area of expertise

1

Pancreatic Cancer

Antony Ruggeri has run 4 trials for Pancreatic Cancer. Some of their research focus areas include:

Stage IV
Stage III
DPD negative
2

Colon Cancer

Antony Ruggeri has run 4 trials for Colon Cancer. Some of their research focus areas include:

Stage IV
Stage III
BRAF negative

Affiliated Hospitals

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Aurora Cancer Care-Milwaukee West

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Aurora BayCare Medical Center

Clinical Trials Antony Ruggeri is currently running

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Selumetinib + Olaparib

for Ovarian and Endometrial Cancer

This phase II ComboMATCH treatment trial compares selumetinib plus olaparib to selumetinib alone in women with endometrial or ovarian (fallopian tube and primary peritoneal) cancer that has come back (recurrent) or that remains despite treatment (persistent) and harbors a mutation in the RAS pathway. Selumetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when it becomes damaged. Blocking PARP may help keep tumor cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. The addition of olaparib to selumetinib could increase the percentage of tumors that shrink as well as lengthen the time that the tumors remain stable (without progression) as compared to selumetinib alone.

Recruiting

1 award

Phase 2

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Targeted Therapy

for Advanced Stage Cancer

The purpose of the study is to learn from the real world practice of prescribing targeted therapies to patients with advanced cancer whose tumor harbors a genomic variant known to be a drug target or to predict sensitivity to a drug. NOTE: Due to character limits, the arms section does NOT include all TAPUR Study relevant biomarkers. For additional information, contact TAPUR@asco.org, or if a patient, your nearest participating TAPUR site (see participating centers). \*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\* Results in publication or poster presentation format are posted as they become available for individual cohorts at www.tapur.org/news. The results may be accessed at any time. All results will be made available on clinicaltrials.gov at the end of the study. Indexing of available results on PubMed is in progress. \*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*\*

Recruiting

1 award

Phase 2

9 criteria

More about Antony Ruggeri

Clinical Trial Related

5 years of experience running clinical trials · Led 14 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Antony Ruggeri has experience with

  • Paclitaxel
  • Olaparib
  • Capecitabine
  • Fluorouracil
  • Cisplatin
  • Irinotecan

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