André-Guy MARTIN | Radio-oncologue ...

Dr. Andre-Guy Martin

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CHUdeQuebec

Studies Prostate Cancer
Studies Radiation Sickness
6 reported clinical trials
16 drugs studied

Affiliated Hospitals

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CHU De Quebec
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CHU De Quebec-L'Hotel-Dieu De Quebec (HDQ)

Clinical Trials Andre-Guy Martin is currently running

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Relugolix + Radiation

for Advanced-Stage Prostate Cancer

This phase II trial compares the usual treatment of radiation therapy alone to using the study drug, relugolix, plus the usual radiation therapy in patients with castration-sensitive prostate cancer that has spread to limited other parts of the body (oligometastatic). Relugolix is in a class of medications called gonadotropin-releasing hormone (GnRH) receptor antagonists. It works by decreasing the amount of testosterone (a male hormone) produced by the body. It may stop the growth of cancer cells that need testosterone to grow. Radiation therapy uses high-energy x rays or protons to kill tumor cells. The addition of relugolix to the radiation may reduce the chance of oligometastatic prostate cancer spreading further.
Recruiting0 awards Phase 2
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Ultra-Hypofractionated Radiotherapy + Brachytherapy

for Prostate Cancer

Phase 1-2 study, comparing ultra-hypofractionnated (UH) to a moderately hypofractionnated (MH) radiation therapy, with image guided HDR prostate brachytherapy. Using iso-equivalent doses, a non-inferiority analysis will be done in order to prove UH non-inferior to MH, toxicity wise. Acceptability, tolerability, acute and late toxicity will be reported. MRI visible dominant intra-prostatic lesion will be outlines and variability between radiation oncologists and radiologists will be reported. As secondary objective, biochemical and clinical failure free survival will be reported at 5 \& 10 years.
Recruiting1 award N/A

More about Andre-Guy Martin

Clinical Trial Related5 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Andre-Guy Martin has experience with
  • HDR Brachytherapy Boost
  • Hypofraction
  • Standard
  • Moderately Hypofractionnated Radiotherapy
  • Ultra Hypofractionnated Radiotherapy
  • Conventionally Fractionated IMRT With HDR Boost

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