Dr. Amy D. Tiersten
Claim this profileIcahn School of Medicine at Mount Sinai Division of Hematology and Medical Oncology
Studies Breast Cancer
Studies Breast cancer
10 reported clinical trials
19 drugs studied
Area of expertise
1Breast Cancer
Stage IV
ER positive
HER2 positive
2Breast Cancer
HER2 positive
Stage IV
ER positive
Affiliated Hospitals
Clinical Trials Amy D. Tiersten is currently running
Lasofoxifene and Abemaciclib vs Fulvestrant and Abemaciclib
for Breast Cancer
The goal of this clinical trial is to assess the efficacy, safety and tolerability of the combination of lasofoxifene and abemaciclib compared to fulvestrant and abemaciclib for the treatment of pre- and postmenopausal women and men who have previously received ribociclib or palbociclib-based treatment and have locally advanced or metastatic estrogen receptor positive (ER+)/human epidermal growth factor 2 negative (HER2-) breast cancer with an estrogen receptor 1 (ESR1) mutation. The main question the study aims to answer is: • To compare the efficacy of the combination of lasofoxifene and abemaciclib with that of fulvestrant and abemaciclib Participants will receive either receive 5 mg/d of oral lasofoxifene plus oral abemaciclib 150 mg twice a day or the combination of fulvestrant 500 mg intramuscular (IM) on Days 1, 15, and 29 and then once monthly thereafter plus oral abemaciclib 150 mg twice a day.
Recruiting2 awards Phase 312 criteria
Sacituzumab + Cisplatin
for Ovarian and Uterine Cancer
This is an open-label, Phase 1 study with a dose expansion cohort of Sacituzumab Govitecan in Combination with Cisplatin in Platinum Sensitive Recurrent Ovarian and Endometrial Cancer. The goal of the study is to determine the optimal dose of sacituzumab govitecan for use in combination with cisplatin for treatment of epithelial ovarian and endometrial cancers.
Recruiting1 award Phase 1 & 29 criteria
More about Amy D. Tiersten
Clinical Trial Related1 year of experience running clinical trials · Led 10 trials as a Principal Investigator · 6 Active Clinical TrialsTreatments Amy D. Tiersten has experience with
- Abemaciclib
- Palbociclib
- Pertuzumab
- Trastuzumab
- Carboplatin
- Everolimus
Breakdown of trials Amy D. Tiersten has run
Breast Cancer
Breast cancer
Cancer
Ovarian Cancer
Endometrial Cancer
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