Dr. Alessandro Santin
Claim this profileSmilow Cancer Hospital at Yale New Haven
Studies Ovarian Cancer
Studies Endometrial Cancer
17 reported clinical trials
25 drugs studied
Area of expertise
1Ovarian Cancer
Stage IV
FRα positive
Stage III
2Endometrial Cancer
Stage IV
Stage III
Stage I
Affiliated Hospitals
Clinical Trials Alessandro Santin is currently running
Avutometinib + Defactinib
for Ovarian Cancer
This study will assess the safety and efficacy of avutometinib (VS-6766) in combination with defactinib versus Investigator's choice of treatments (ICT) in subjects with recurrent LGSOC who have progressed on a prior platinum-based therapy.
Recruiting2 awards Phase 38 criteria
Herceptin Hylecta or Phesgo + Chemotherapy
for Uterine Cancer
This phase III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin Hylecta \[TM\]) or pertuzumab, trastuzumab and hyaluronidase-zzxf (Phesgo \[TM\]) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial cancer. Trastuzumab and pertuzumab are monoclonal antibodies and forms of targeted therapy that attach to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When trastuzumab or pertuzumab attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Hyaluronidase is an endoglycosidase. It helps to keep pertuzumab and trastuzumab in the body longer, so that these medications will have a greater effect. Hyaluronidase also allows trastuzumab and trastuzumab/pertuzumab to be given by injection under the skin and shortens their administration time compared to trastuzumab or pertuzumab alone. Paclitaxel is a taxane and in a class of medications called antimicrotubule agents. It stops tumor cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Giving Herceptin Hylecta or Phesgo in combination with paclitaxel and carboplatin may shrink the tumor and prevent the cancer from coming back in patients with HER2 positive endometrial cancer.
Recruiting2 awards Phase 3
More about Alessandro Santin
Clinical Trial Related5 years of experience running clinical trials · Led 17 trials as a Principal Investigator · 5 Active Clinical TrialsTreatments Alessandro Santin has experience with
- Carboplatin
- Paclitaxel
- Sacituzumab Govitecan
- Pembrolizumab
- Topotecan
- Mirvetuximab Soravtansine
Breakdown of trials Alessandro Santin has run
Ovarian Cancer
Endometrial Cancer
Fallopian Tube Cancer
Uterine Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Alessandro Santin specialize in?
Alessandro Santin focuses on Ovarian Cancer and Endometrial Cancer. In particular, much of their work with Ovarian Cancer has involved Stage IV patients, or patients who are FRα positive.
Is Alessandro Santin currently recruiting for clinical trials?
Yes, Alessandro Santin is currently recruiting for 5 clinical trials in New Haven Connecticut. If you're interested in participating, you should apply.
Are there any treatments that Alessandro Santin has studied deeply?
Yes, Alessandro Santin has studied treatments such as Carboplatin, Paclitaxel, Sacituzumab Govitecan.
What is the best way to schedule an appointment with Alessandro Santin?
Apply for one of the trials that Alessandro Santin is conducting.
What is the office address of Alessandro Santin?
The office of Alessandro Santin is located at: Smilow Cancer Hospital at Yale New Haven, New Haven, Connecticut 06520 United States. This is the address for their practice at the Smilow Cancer Hospital at Yale New Haven.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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