Dr. Adam J. Olszewski, MD | Providence ...

Dr. Adam J. Olszewski

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Rhode Island Hospital

Studies Mantle Cell Lymphoma
Studies Lymphoma
11 reported clinical trials
25 drugs studied

Area of expertise

1Mantle Cell Lymphoma
Adam J. Olszewski has run 5 trials for Mantle Cell Lymphoma. Some of their research focus areas include:
t(11;14) positive
CCND1 positive
Stage I
2Lymphoma
Adam J. Olszewski has run 5 trials for Lymphoma. Some of their research focus areas include:
CD10 positive
BCL6 positive
CXCL13 positive

Affiliated Hospitals

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Rhode Island Hospital
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Lifespan Cancer Institute At Rhode Island Hospital

Clinical Trials Adam J. Olszewski is currently running

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Rituximab vs Mosunetuzumab

for Follicular Lymphoma

This phase III trial compares the effectiveness of rituximab to mosunetuzumab in treating patients with follicular lymphoma with a low tumor burden. Rituximab is a monoclonal antibody. It binds to a protein called CD20, which is found on B cells (a type of white blood cell) and some types of cancer cells. This may help the immune system kill cancer cells. Mosunetuzumab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread. It is not yet known if giving rituximab or mosunetuzumab works better in treating patients with follicular lymphoma with a low tumor burden.
Recruiting2 awards Phase 313 criteria
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Zanubrutinib

for Mantle Cell Lymphoma

This phase III trial tests whether continuous or intermittent zanubrutinib after achieving a complete remission (CR) with rituximab works in older adult patients with mantle cell lymphoma (MCL) who have not received treatment in the past (previously untreated). Rituximab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread. Zanubrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. When zanubrutinib is used in MCL, the current standard of care is to continue administering the drug indefinitely until disease progression. This continuous treatment comes with clinical as well as financial toxicity, which could be especially detrimental in older patients. For patients who achieve a CR after initial zanubrutinib plus rituximab therapy, it may be safe and equally effective to stop treatment and restart zanubrutinib upon disease progression rather than continuing indefinitely in previously untreated older adult patients with MCL.
Recruiting2 awards Phase 310 criteria

More about Adam J. Olszewski

Clinical Trial Related4 years of experience running clinical trials · Led 11 trials as a Principal Investigator · 5 Active Clinical Trials
Treatments Adam J. Olszewski has experience with
  • Rituximab
  • Cyclophosphamide
  • Mosunetuzumab
  • SGR-1505
  • Chemotherapy
  • CDX-1140

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