Breast Cancer Clinical Trials 2023

Breast Cancer studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect breast cancer clinical trial in 2023.

Reviewed by Michael Gill, B. Sc.
Image of Smilow Cancer Hospital at Yale - New Haven in New Haven, United States.
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

PF-07220060for Liposarcoma

18 - 99
All Sexes
New Haven, CT
This trial is testing a new drug, PF-07220060, to see if it is safe and effective when used alone or in combination with other drugs. The trial will be conducted in four parts, with escalating doses in the first part to determine the maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D). The second part of the trial will test the drug in combination with two different endocrine therapies (letrozole and fulvestrant). The third part of the trial will assess the food effect of the RP2D dose from Part 1A. The fourth part of the trial will be an expansion for combination
Phase 1
Recruiting
Smilow Cancer Hospital at Yale - New Haven (+8 Sites)Pfizer CT.gov Call CenterPfizer
Image of Albert Einstein Medical Center Montgomery in East Norriton, United States.
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

Parallel Placementfor Breast Cancer

18+
All Sexes
East Norriton, PA
This trial is testing whether in-line or perpendicular placement of Steri-Strips on breast surgery incisions affects healing. Patients' age, comorbid conditions, type of breast surgery, and treatment with pre-operative or post-operative chemotherapy or radiation therapy will be reviewed to ensure similar study groups. Steri-Strips will be allowed to fall off naturally and pictures will be taken of the incisional area at 30-day and 90-day follow-ups. A blinded, independent surgeon will grade each incision according to the modified Hollander Cosmesis Scale. Statistical analysis will be performed to determine significance of the
Recruiting
Has No Placebo
Albert Einstein Medical Center Montgomery (+1 Sites)Candace L Ward, MD, MPH
10 Breast Cancer Clinical Trials Near Me

What Are Breast Cancer Clinical Trials?

Breast cancer is a cancer that forms in the cells of breasts. Breast cancer symptoms can vary from swollen lymph nodes to a new lump in the breast or armpit. Breast cancer may spread into the surronding tissues if the disease progresses.

In clinical trials, men and women with all types and stages of breast cancer participate in helping doctors and scientists find better treatment methods and medication. In addition, many researchers are looking at innovative therapeutics to determine if they are safe, effective, or even better than standard treatments.

Why Is Breast Cancer Being Studied Through Clinical Trials?

Recent statistics from 2020 have shown a significant increase in women's breast cancer. In addition, breast cancer is now the most diagnosed type of cancer, with 1 in every 3 women diagnosed.

Clinical studies focus on trying out new drugs (medication), different treatment plans, advanced surgery and radiation methods, and various other types of therapy.

What Are The Types of Treatments Available For Breast Cancer?

A breast cancer diagnosis is confirmed by taking a biopsy of the concerned tissue. How breast cancer is treated varies on its type and stage. These treatments include surgery, chemotherapym hormone therapy, targeted drugs, and immunotherapy, and a combination of these are used to treat breast cancer patients.

What Are Some Recent Breakthrough Clinical Trials For Breast Cancer?

There has been several landmark studies involving breast cancer in recent years. Some of the most notable studies are:

2023: Pembrolizumab Improves Survival in Advanced Triple-Negative Breast Cancer The Institute of Cancerology Strasbourg, Strasbourg, France, found that combining chemotherapy with the immunotherapy medicine pembrolizumab (Keytruda) can extend the lives of certain patients with advanced triple-negative breast cancer. This is significant because, in general, triple-negative breast cancer is more aggressive, harder to cure, and recurring than other forms of the disease.

2023: Enhertu Improves Survival for Metastatic “HER2-Low” Breast Cancer The Memorial Sloan Kettering Cancer Center found that trastuzumab deruxtecan (Enhertu), used for the treatment of HER2-low breast cancers, can prolong the life of the patients by up to 6 months. This is significant because the FDA approved this drug for people who had previously received chemotherapy or had their cancer returned within 6 months of surgery or completion of chemotherapy.

Who Are Some Of The Key Opinion Leaders / Researchers / Institutions Conducting Breast Cancer

Dr. Shanu Modi, M.D

Shanu Modi, M.D is a medical oncologist at Memorial Sloan Kettering Cancer Center. Her research focuses on the clinical development of new breast cancer treatments, emphasizing evaluating targeted biological anticancer drugs.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 27th, 2021

Last Reviewed: February 14th, 2023