Veterans Affairs Medical Center - Long Beach

Summary

Veterans Affairs Medical Center - Long Beach is a medical facility located in Long Beach, California. This center is recognized for care of Lung Cancer, Prostate Cancer, Cancer, Hepatitis C, Diabetes and other specialties. Veterans Affairs Medical Center - Long Beach is involved with conducting 273 clinical trials across 358 conditions. There are 19 research doctors associated with this hospital, such as Pankaj Gupta, Michael Hollifield, MD, Helen Ma, MD, and Kamyar Kalantar-Zadeh, MD PhD.

Top PIs

Clinical Trials running at Veterans Affairs Medical Center - Long Beach

Prostate Cancer

Lung Cancer

Bladder Cancer

Pancreatic Cancer

Non-Small Cell Lung Cancer

Cancer

Ovarian Cancer

Lymphoma

Breast Cancer

Colorectal Cancer

Carboplatin + Cabazitaxel

for Prostate Cancer

This phase III trial compares the effect of adding carboplatin to the standard of care chemotherapy drug cabazitaxel versus cabazitaxel alone in treating prostate cancer that keeps growing even when the amount of testosterone in the body is reduced to very low levels (castrate-resistant) and that has spread from where it first started (primary site) to other places in the body (metastatic). Carboplatin is in a class of medications known as platinum-containing compounds. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Chemotherapy drugs, such as cabazitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Prednisone is often given together with chemotherapy drugs. Prednisone is in a class of medications called corticosteroids. It is used to reduce inflammation and lower the body's immune response to help lessen the side effects of chemotherapy drugs and to help the chemotherapy work. Giving carboplatin with the standard of care chemotherapy drug cabazitaxel may be better at treating metastatic castrate-resistant prostate cancer.

Recruiting

2 awards

Phase 3

5 criteria

Standard Therapy + Surgery/Radiation

for Prostate Cancer

This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for prostate cancer may lower the chance of the cancer growing or spreading.

Recruiting

2 awards

Phase 3

30 criteria

Apalutamide + Hormone and Radiation Therapies

for Prostate Cancer

This phase III trial studies whether adding apalutamide to the usual treatment improves outcome in patients with lymph node positive prostate cancer after surgery. Radiation therapy uses high energy x-ray to kill tumor cells and shrink tumors. Androgens, or male sex hormones, can cause the growth of prostate cancer cells. Drugs, such as apalutamide, may help stop or reduce the growth of prostate cancer cell growth by blocking the attachment of androgen to its receptors on cancer cells, a mechanism similar to stopping the entrance of a key into its lock. Adding apalutamide to the usual hormone therapy and radiation therapy after surgery may stabilize prostate cancer and prevent it from spreading and extend time without disease spreading compared to the usual approach.

Recruiting

2 awards

Phase 3