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Vanderbilt-Ingram Cancer Center

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Nashville, Tennessee 37212

Global Leader in Cancer

Global Leader in Lung Cancer

Conducts research for Breast Cancer

Conducts research for Solid Tumors

Conducts research for Pancreatic Cancer

1090 reported clinical trials

68 medical researchers

Photo of Vanderbilt-Ingram Cancer Center in NashvillePhoto of Vanderbilt-Ingram Cancer Center in NashvillePhoto of Vanderbilt-Ingram Cancer Center in Nashville

Summary

Vanderbilt-Ingram Cancer Center is a medical facility located in Nashville, Tennessee. This center is recognized for care of Cancer, Lung Cancer, Breast Cancer, Solid Tumors, Pancreatic Cancer and other specialties. Vanderbilt-Ingram Cancer Center is involved with conducting 1,090 clinical trials across 858 conditions. There are 68 research doctors associated with this hospital, such as Scott Borinstein, M.D., Michael Gibson, Elizabeth J. Davis, and Debra L. Friedman.

Area of expertise

1

Cancer

Global Leader

Vanderbilt-Ingram Cancer Center has run 182 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
Stage I
2

Lung Cancer

Global Leader

Vanderbilt-Ingram Cancer Center has run 128 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
Stage II

Top PIs

Clinical Trials running at Vanderbilt-Ingram Cancer Center

Lung Cancer

Cancer

Skin Cancer

Kidney Cancer

Breast Cancer

Ovarian Cancer

Colorectal Cancer

Prostate Cancer

Multiple Myeloma

Solid Tumors

Image of trial facility.

N-803 + Tislelizumab + Docetaxel

for Non-Small Cell Lung Cancer

This is a randomized, open-label, phase 3 clinical trial to compare the efficacy and safety of N-803 plus tislelizumab and docetaxel (experimental arm) versus docetaxel monotherapy (control arm). Enrolled participants will be randomized 2:1 to treatment in the experimental arm or the control arm. Participant randomization will be stratified by geographical region (North America vs Europe vs ASIA vs Other), NSCLC histology (squamous vs nonsquamous), and actionable genomic alteration (AGA); (epidermal growth factor receptor \[EGFR\]/anaplastic lymphoma kinase \[ALK\] vs OTHER AGA vs No AGA).

Recruiting

2 awards

Phase 3

5 criteria

Image of trial facility.

Radiotherapy

for Lung Cancer

This study is being done to answer the following question: Can the chance of lung cancer growing or spreading be lowered by adding targeted radiotherapy to the usual combination of drugs? This study is being done to find out if this approach is better or worse than the usual approach for lung cancer. The usual approach is defined as the care most people get for non-small cell lung cancer.

Recruiting

2 awards

Phase 3

4 criteria

Image of trial facility.

Osimertinib + Bevacizumab

for Lung Cancer

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.

Recruiting

2 awards

Phase 3

31 criteria

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