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University of South Carolina

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Columbia, South Carolina 29208
Global Leader in Obesity
Conducts research for Childhood Obesity
Conducts research for Human Immunodeficiency Virus Infection
Conducts research for Physical Activity
Conducts research for Stroke
121 reported clinical trials
7 medical researchers
Photo of University of South Carolina in ColumbiaPhoto of University of South Carolina in ColumbiaPhoto of University of South Carolina in Columbia

Summary

University of South Carolina is a medical facility located in Columbia, South Carolina. This center is recognized for care of Obesity, Childhood Obesity, Human Immunodeficiency Virus Infection, Physical Activity, Stroke and other specialties. University of South Carolina is involved with conducting 121 clinical trials across 242 conditions. There are 7 research doctors associated with this hospital, such as Christine Pellegrini, Ph.D., Brie Turner-McGrievy, PhD, MS, RD, Souvik Sen, and Bernardine M Pinto, PhD.

Top PIs

Clinical Trials running at University of South Carolina

Obesity
Stroke
Health Behaviors
Chronic Kidney Disease
Type 2 Diabetes
Aphasia
Colorectal Cancer
Arthritis
Knee Arthropathy
Antibiotic Prophylaxis
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Digital Weight Loss Interventions

for Obesity

Over 130 million adults in the US experience overweight and obesity, and rural communities experience significantly higher rates of obesity and related chronic diseases. Although lifestyle interventions successfully produce clinically significant weight losses, the availability of weight management programs is limited in rural areas. Digital interventions offer an attractive alternative for delivering lifestyle programs to rural populations. However, in-person behavioral obesity treatment programs achieve better weight losses than digital programs, likely because in-person programs typically include personnel-intensive "high touch" treatment components. Some studies indicate that having a human "behind the curtain" of a digital program through emailed feedback or with the addition of online group sessions can significantly increase weight loss. Therefore, the aims of this study are to increase the public health impact of digital obesity treatment for rural populations by simultaneously investigating 3 "high touch" intervention components. The investigators will conduct a highly efficient experiment with participants residing in non-urban areas recruited online from across the United States. Participants (N=616; 22% racial/ethnic minority; 40% male) will be randomized to: (1) weekly facilitated synchronous group video sessions (yes vs. no); (2) type of self-monitoring feedback received (counselor-crafted vs. pre-scripted); and (3) individual coaching calls (yes vs. no). These components will be layered onto our 24-week evidence-based, interactive digital weight loss program delivered to groups of eligible individuals. Based on the results of the experiment, The investigators will identify an optimized program in which each component (or combination of components) contributes meaningfully (at least 1.5 kg greater weight loss at 6-months) to enhanced weight loss. The investigators will also exploratory analyses of weight trajectories 6-months post-treatment (i.e., at 12-months) to elucidate extended impact of the specific components on weight control. Ultimately, this research will set the stage for confirming the most promising digital behavioral weight loss intervention that can be used without geographic borders to reduce obesity rates among rural residents and provide the evidence needed to establish best practice policies for broadly effective digital approaches to weight control.
Recruiting1 award N/A6 criteria
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Dietary Interventions

for Type 2 Diabetes

Based on the findings of our formative work, conduct a one-year intervention among African American Adults using revised culturally tailored materials to examine differences in Healthy Eating Index (HEI) and type 2 diabetes (T2DM) risk factors among participants (n=198) randomized to one of the 3 dietary patterns: 1) Healthy U.S.-Style Eating Pattern, 2) Healthy Mediterranean-Style Eating Pattern, and 3) Healthy Vegetarian Eating Pattern.
Recruiting1 award N/A7 criteria
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"GameDay Ready" Program

for Obesity

This pilot study investigates the effects of a newly developed 12-week weight management program called "GameDay Ready" (compared to a walking and general health education program) for decreasing body weight among Black men who live in the rural South. The researchers expect to see evidence of greater weight loss among participants randomized to receive the "GameDay Ready" program.
Recruiting1 award N/A6 criteria

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Frequently asked questions

What kind of research happens at University of South Carolina?
University of South Carolina is a medical facility located in Columbia, South Carolina. This center is recognized for care of Obesity, Childhood Obesity, Human Immunodeficiency Virus Infection, Physical Activity, Stroke and other specialties. University of South Carolina is involved with conducting 121 clinical trials across 242 conditions. There are 7 research doctors associated with this hospital, such as Christine Pellegrini, Ph.D., Brie Turner-McGrievy, PhD, MS, RD, Souvik Sen, and Bernardine M Pinto, PhD.