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University of Kansas Medical Center

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Kansas City, Kansas 66103

Global Leader in Parkinson's Disease

Global Leader in Breast Cancer

Conducts research for Heart Failure

Conducts research for Cystic Fibrosis

Conducts research for Stroke

1261 reported clinical trials

88 medical researchers

Photo of University of Kansas Medical Center in Kansas CityPhoto of University of Kansas Medical Center in Kansas CityPhoto of University of Kansas Medical Center in Kansas City

Summary

University of Kansas Medical Center is a medical facility located in Kansas City, Kansas. This center is recognized for care of Parkinson's Disease, Breast Cancer, Heart Failure, Cystic Fibrosis, Stroke and other specialties. University of Kansas Medical Center is involved with conducting 1,261 clinical trials across 1,274 conditions. There are 88 research doctors associated with this hospital, such as Dhanunjaya Lakkireddy, Jeffrey Statland, Andrea D. Jewell, and Rajesh Pahwa.

Area of expertise

1

Parkinson's Disease

Global Leader

University of Kansas Medical Center has run 57 trials for Parkinson's Disease. Some of their research focus areas include:

Stage II
Stage I
Stage III
2

Breast Cancer

Global Leader

University of Kansas Medical Center has run 48 trials for Breast Cancer. Some of their research focus areas include:

Stage III
HER2 positive
Stage IV

Top PIs

Clinical Trials running at University of Kansas Medical Center

Heart Failure

Stroke

Cystic Fibrosis

Smoking Cessation

Multiple Myeloma

Lung Cancer

Obesity

Pulmonary Hypertension

Parkinson's Disease

Prostate Cancer

Image of trial facility.

Reprieve System

for Heart Failure

The objective of this study is to prospectively compare decongestive therapy administered by the Reprieve System to Optimal Diuretic Therapy (ODT) in the treatment of patients diagnosed with acute decompensated heart failure (ADHF). The main objective is to determine if the Reprieve System can more efficiently decongest ADHF patients in comparison to Control Therapy.

Recruiting

2 awards

Phase 3

3 criteria

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HeartMate 3 Device

for Heart Failure

Durable left ventricular assist devices (dLVAD) have been increasingly utilized since the mid to late 1990s, with an uptick of utility starting in 2010 following expanded indications for therapy to not only include a bridge to transplantation strategy, but also for those individuals who suffer from advanced heart failure (HF) and do not qualify for cardiac transplantation. Despite the decreasing size of the newest generation devices leading to a lessened occurrence of adverse events, bleeding and infection still remain a concern for clinicians, as well as a general lack of predictability towards adverse events in individuals with a dLVAD in place. There is a lack of description in the literature currently, regarding the interface between what the pump data provides and what is seen in clinical practice. There also is little known about the effects of what is provided in the pump data, in correlation to quality-of-life following dLVAD implantation. Therefore, the purpose of this study is to prospectively analyze normal and abnormal pump data through pump operations such as suction events, low flow alarms as well as other adventitious alarms, PI events and power cable disconnects greater than 20 seconds, from the HeartMate 3 ® dLVAD in order to clinically correlate this data to quality of life, frailty and other various medical conditions and adverse events as defined by the Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs). This will be achieved through two aims: 1) Evaluate the effectiveness of dLVAD pump operations data on clinical practice application (quality of life, frailty and various medical conditions, and adverse events such as GIB, RHF, infection, hypertension, arrhythmias and stroke); and 2) Evaluate correlations and relationships of longitudinal normal and abnormal dLVAD pump operations data, to demographic and clinical variables. This study is the first study to evaluate HeartMate 3 ® dLVAD pump operations data over time for effectiveness in the clinical practice.

Recruiting

1 award

N/A

2 criteria

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Levosimendan

for Pulmonary Hypertension with Heart Failure

This study will evaluate the efficacy of TNX-103 (oral levosimendan) compared with placebo in subjects with PH-HFpEF as measured by the change in 6-Minute Walk Distance (6 MWD; Day 1 to Week 12).

Recruiting

1 award

Phase 3

10 criteria

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