The Cancer Institute of New Jersey Hamilton

Summary

The Cancer Institute of New Jersey Hamilton is a medical facility located in Trenton, New Jersey. This center is recognized for care of Breast Cancer, Lung Cancer, Breast cancer, Colon Cancer, Prostate Cancer and other specialties. The Cancer Institute of New Jersey Hamilton is involved with conducting 94 clinical trials across 91 conditions. There are 12 research doctors associated with this hospital, such as Howard S. Hochster, Eugenia Girda, MD, Missak Haigentz, MD, and Mridula George, MD.

Top PIs

Clinical Trials running at The Cancer Institute of New Jersey Hamilton

Breast Cancer

Ovarian Cancer

Lung Cancer

Breast cancer

Small Cell Lung Cancer

Kidney Cancer

Oropharyngeal Carcinoma

Renal Cell Carcinoma

Colon Cancer

Oral Squamous Cell Carcinoma

Omitting Radiation Therapy

for Breast Cancer

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming back.

Recruiting

2 awards

Phase 3

19 criteria

Pembrolizumab

for Triple-Negative Breast Cancer

The phase III trial compares the effect of pembrolizumab to observation for the treatment of patients with early-stage triple-negative breast cancer who achieved a pathologic complete response after preoperative chemotherapy in combination with pembrolizumab. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial may help researchers determine if observation will result in the same risk of cancer coming back as pembrolizumab after surgery in triple-negative breast cancer patients who achieve pathologic complete response after preoperative chemotherapy with pembrolizumab.

Recruiting

2 awards

Phase 3

19 criteria

Durvalumab + Chemotherapy

for Breast Cancer

This phase III trial compares the addition of an immunotherapy drug (durvalumab) to usual chemotherapy versus usual chemotherapy alone in treating patients with MammaPrint High 2 Risk (MP2) stage II-III hormone receptor positive, HER2 negative breast cancer. Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as paclitaxel, doxorubicin, and cyclophosphamide work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. There is some evidence from previous clinical trials that people who have a MammaPrint High 2 Risk result may be more likely to respond to chemotherapy and immunotherapy. Adding durvalumab to usual chemotherapy may be able to prevent the cancer from returning for patients with MP2 stage II-III hormone receptor positive, HER2 negative breast cancer.

Recruiting

2 awards

Phase 3

40 criteria