South Denver Cardiology Associates PC

Summary

South Denver Cardiology Associates PC is a medical facility located in Littleton, Colorado. This center is recognized for care of Heart Failure, Atrial Fibrillation, Coronary Artery Disease, Stroke, Arrhythmia and other specialties. South Denver Cardiology Associates PC is involved with conducting 57 clinical trials across 74 conditions. There are 6 research doctors associated with this hospital, such as Ira Dauber, MD, Lee MacDonald, MD, Sri Sundaram, and Cinthia Bateman, MD.

Top PIs

Clinical Trials running at South Denver Cardiology Associates PC

Atrial Fibrillation

Heart Failure

Stroke

Bleeding

Hemorrhage

Heart disease

Coronary artery disease

Arrhythmia

Atrial Flutter

Catheter Ablation + HF Therapies

for Heart Failure and Atrial Fibrillation

Heart failure (HF) with preserved left ventricular function (pEF) is difficult clinical syndrome to treat effectively with few evidence based therapies. Atrial fibrillation (AF) is now an important co-morbidity being observed in 43% of patients with HFpEF. Rhythm control has not been studied in this population. Catheter ablation and antiarrhythmic drugs are rhythm control therapies that have been used for treatment of AF without HF or HF with reduced systolic function but have not been widely applied in HFpEF. No controlled comparative evaluation has been performed in HFpEF. The introduction of wireless pulmonary artery hemodynamic monitoring has permitted optimization of HF therapy in patients with chronic HF with reduced and preserved EF. Reduction in HF hospitalizations has been observed in post hoc analyses of HFpEF patients but has not been systematically applied in AF patients with HFpEF. In this study, we propose to study both rhythm control and optimized HF therapeutic approaches in an AF with HFpEF study population in a pilot study using a sequential two phase randomized controlled clinical trial design.

Recruiting

3 awards

Phase 4

13 criteria

Smartwatch-Guided DOAC Therapy

for Atrial Fibrillation

This trial tests whether taking blood-thinning medication continuously or only when a smart watch detects an irregular heartbeat is better for adults with a history of irregular heartbeats and moderate stroke risk.

Recruiting

2 awards

Phase 3

5 criteria

Left Atrial Appendage Occlusion vs. NOAC

for Atrial Fibrillation

The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Control Group"). The choice of NOAC in the Control Group will be left to study physician discretion.

Recruiting

1 award

N/A

8 criteria