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Providence Saint John's Health Center

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Santa Monica, California 90404
Conducts research for Melanoma
Conducts research for Bladder Cancer
Conducts research for Breast Cancer
Conducts research for Cancer
Conducts research for Solid Tumors
38 reported clinical trials
8 medical researchers
Photo of Providence Saint John's Health Center in Santa MonicaPhoto of Providence Saint John's Health Center in Santa MonicaPhoto of Providence Saint John's Health Center in Santa Monica

Summary

Providence Saint John's Health Center is a medical facility located in Santa Monica, California. This center is recognized for care of Melanoma, Bladder Cancer, Breast Cancer, Cancer, Solid Tumors and other specialties. Providence Saint John's Health Center is involved with conducting 38 clinical trials across 102 conditions. There are 8 research doctors associated with this hospital, such as Santosh Kesari, MD, Naveed Wagle, MD, Parvin Peddi, MD, and Orrin Troum, MD.

Area of expertise

1Melanoma
Providence Saint John's Health Center has run 8 trials for Melanoma. Some of their research focus areas include:
Stage IV
Stage III
BRAF positive
2Bladder Cancer
Providence Saint John's Health Center has run 6 trials for Bladder Cancer. Some of their research focus areas include:
Stage IV
Stage III

Top PIs

Clinical Trials running at Providence Saint John's Health Center

Cancer
Solid Tumors
Skin Cancer
Ovarian Cancer
Breast Cancer
Liver Cancer
Urothelial Carcinoma
Hematologic Malignancies
Prostate Cancer
Renal Cell Carcinoma
Image of trial facility.

MDNA11 + Pembrolizumab

for Cancer

This is a Phase 1/2, multi-center, open-label, dose-escalation and expansion study to evaluate safety and tolerability, PK, pharmacodynamic, and early signal of anti-tumor activity of MDNA11 alone or in combination with a checkpoint inhibitor in patients with advanced solid tumors.
Recruiting1 award Phase 1 & 2
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Emavusertib +/- Ibrutinib

for CNS Lymphoma

This is a multi-center, open-label study to evaluate the safety, pharmacokinetics (PK), and anti-cancer activity of oral administration of emavusertib alone or in combination with ibrutinib in adult participants with relapsed or refractory (R/R) hematologic malignancies. This trial will be completed in four parts. In Part A1, emavusertib will be evaluated first in a dose escalating monotherapy setting to establish the safety and tolerability (complete). In Part A2, emavusertib will be evaluated in combination with ibrutinib at 560 milligrams (mg) once daily (QD) or 420 mg QD as indicated by disease (Part A2 complete). Part B will comprise 2 cohorts to assess safety and efficacy of emavusertib in combination with ibrutinib in participants with R/R primary central nervous system lymphoma (PCNSL) who have directly progressed on a bruton tyrosine kinase inhibitor (BTKi). In this part of the study, emavusertib will be dosed at 100 mg or 200 mg twice daily (BID) in combination with ibrutinib in 28-day treatment cycles. Part C will comprise 3 treatment arms in the second-line setting to assess the efficacy and safety of emavusertib monotherapy, ibrutinib monotherapy, and emavusertib in combination with ibrutinib in participants with R/R PCNSL who are naïve to BTKi treatment. In this part of the study, eligible second-line participants with R/R PCNSL who are naïve to BTKi treatment will be randomized 1:1:1 to 1 of 3 treatment arms: (1) emavusertib 200 mg BID, (2) ibrutinib 560 mg QD, or (3) emavusertib 200 mg BID in combination with ibrutinib 560 mg QD.
Recruiting1 award Phase 1 & 21 criteria
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AdAPT-001

for Cancer

AdAPT-001 is an oncolytic virus that is injected directly into the tumor or via intraarterial administration. The purpose of this study is to find out if AdAPT-001 is safe and tolerable. The next step is to find out if AdAPT-001 if efficacious with or without a checkpoint inhibitor.
Recruiting1 award Phase 217 criteria

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Frequently asked questions

What kind of research happens at Providence Saint John's Health Center?
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security