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NeuroTrials Research Inc.
Claim this profileAtlanta, Georgia 30342
Global Leader in Narcolepsy
Global Leader in Obstructive Sleep Apnea
Conducts research for Excessive Daytime Sleepiness
Conducts research for Sleep Apnea Syndrome
Conducts research for Excessive Sleepiness
103 reported clinical trials
1 medical researcher
Summary
NeuroTrials Research Inc. is a medical facility located in Atlanta, Georgia. This center is recognized for care of Narcolepsy, Obstructive Sleep Apnea, Excessive Daytime Sleepiness, Sleep Apnea Syndrome, Excessive Sleepiness and other specialties. NeuroTrials Research Inc. is involved with conducting 103 clinical trials across 96 conditions. There are 1 research doctors associated with this hospital, such as Russell P. Rosenberg.Area of expertise
1Narcolepsy
Global LeaderHLA positive
HLA-DQB1
CSF orexin
2Obstructive Sleep Apnea
Global LeaderTop PIs
Clinical Trials running at NeuroTrials Research Inc.
Obstructive Sleep Apnea
Narcolepsy
Migraine
Insomnia
Obsessive-Compulsive Disorder
Excessive Daytime Sleepiness
Sleep Apnea
Anxiety Disorder
Anxiety
Hypertension
IHL-42X
for Obstructive Sleep Apnea
The goal of this randomised, double-blind phase II/III clinical trial is to determine the safety and efficacy of IHL-42X in subjects with obstructive sleep apnoea who are intolerant, non-compliant, or naïve to positive airway pressure. Phase II study will be a 4-week dose-finding study comparing two dose strengths of IHL-42X to placebo. The optimal dose strength will be selected based on comparing the safety and efficacy of the two IHL-42X dose strengths to placebo over a 4-week treatment period. The three treatment groups are; IHL-42X Low dose (2.5mg dronabinol, 125mg acetazolamide), IHL-42X High dose (5mg dronabinol, 250mg acetazolamide) and Placebo. Each treatment group will enrol approximately 40 patients per treatment arm, for a total of approximately 120 patients. The safety and efficacy results of the Phase II study will be used to select the dose strength of IHL-42X and corresponding doses of dronabinol and acetazolamide in Phase III. Phase III study will use the optimal dose strength of IHL-42X identified in Phase II and will be compared to the component active pharmaceutical ingredients at equivalent dose strengths to those found in the IHL-42X optimal dose strength and placebo over 52 weeks. The four treatment groups are; IHL-42X (optimal dose from Phase II), Acetazolamide (equivalent dose strength to that in the IHL-42X optimal dose strength), Dronabinol (equivalent dose strength to that in the IHL-42X optimal dose strength) and placebo. The treatment groups will enrol approximately 165 patients in IHL-42X, approximately 55 patients in dronabinol, approximately 55 in acetazolamide, and approximately 165 in placebo, for a total of approximately 440 patients.
Recruiting0 awards Phase 2 & 3
Lorundrostat
for Obstructive Sleep Apnea and High Blood Pressure
The primary purpose of the study is to assess the effect of lorundrostat taken orally (po) once a day on the Apnea-Hypopnea Index (AHI) in participants with moderate to severe obstructive sleep apnea (OSA) and hypertension.
Recruiting0 awards Phase 22 criteria
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Frequently asked questions
What kind of research happens at NeuroTrials Research Inc.?
NeuroTrials Research Inc. is a medical facility located in Atlanta, Georgia. This center is recognized for care of Narcolepsy, Obstructive Sleep Apnea, Excessive Daytime Sleepiness, Sleep Apnea Syndrome, Excessive Sleepiness and other specialties. NeuroTrials Research Inc. is involved with conducting 103 clinical trials across 96 conditions. There are 1 research doctors associated with this hospital, such as Russell P. Rosenberg.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.