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Nemours Children's Clinic - Pensacola
Claim this profilePensacola, Florida 32504
Global Leader in Cancer
Global Leader in Brain Tumor
Conducts research for Acute Lymphoblastic Leukemia
Conducts research for Solid Tumors
Conducts research for Neuroblastoma
115 reported clinical trials
0 medical researchers
Summary
Nemours Children's Clinic - Pensacola is a medical facility located in Pensacola, Florida. This center is recognized for care of Cancer, Brain Tumor, Acute Lymphoblastic Leukemia, Solid Tumors, Neuroblastoma and other specialties. Nemours Children's Clinic - Pensacola is involved with conducting 115 clinical trials across 291 conditions. There are 0 research doctors associated with this hospital, such as .Area of expertise
1Cancer
Global LeaderStage IV
Stage I
Stage II
2Brain Tumor
Global LeaderBRAF positive
Stage I
Stage II
Top PIs
Clinical Trials running at Nemours Children's Clinic - Pensacola
Brain Tumor
Testicular cancer
Wilms Tumor
Leukemia
Cancer
Acute Lymphoblastic Leukemia
Burkitt Lymphoma
Biphenotypic Leukemia
Acute Leukemia
Ovarian Carcinoma
Selumetinib vs. Chemotherapy
for Brain Cancer
This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3
Lower Radiotherapy Dose
for Brain Tumors
This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.
Recruiting1 award Phase 210 criteria
Chemotherapy + Radiation Therapy
for Brain Cancer
This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to diminish spinal cord relapses, 2) utilizing higher dose chemotherapy followed by conventional RT in patients who did not respond to induction chemotherapy. Chemotherapy drugs, such as carboplatin, etoposide, ifosfamide, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays or high-energy protons to kill tumor cells and shrink tumors. Studies have shown that patients with newly-diagnosed localized NGGCT, whose disease responds well to chemotherapy before receiving radiation therapy, are more likely to be free of the disease for a longer time than are patients for whom the chemotherapy does not efficiently eliminate or reduce the size of the tumor. The purpose of this study is to see how well the tumors respond to induction chemotherapy to decide what treatment to give next. Some patients will be given RT to the spine and a portion of the brain. Others will be given high dose chemotherapy and a stem cell transplant before RT to the whole brain and spine. Giving treatment based on the response to induction chemotherapy may lower the side effects of radiation in some patients and adjust the therapy to a more efficient one for other patients with localized NGGCT.
Recruiting1 award Phase 2
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Frequently asked questions
What kind of research happens at Nemours Children's Clinic - Pensacola?
Nemours Children's Clinic - Pensacola is a medical facility located in Pensacola, Florida. This center is recognized for care of Cancer, Brain Tumor, Acute Lymphoblastic Leukemia, Solid Tumors, Neuroblastoma and other specialties. Nemours Children's Clinic - Pensacola is involved with conducting 115 clinical trials across 291 conditions. There are 0 research doctors associated with this hospital, such as .
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.