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Johns Hopkins All Children's Hospital
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Saint Petersburg, Florida 33701
Global Leader in Cancer
Global Leader in Brain Tumor
Conducts research for Soft Tissue Sarcoma
Conducts research for Acute Lymphoblastic Leukemia
Conducts research for Leukemia
366 reported clinical trials
19 medical researchers
Summary
Johns Hopkins All Children's Hospital is a medical facility located in Saint Petersburg, Florida. This center is recognized for care of Cancer, Brain Tumor, Soft Tissue Sarcoma, Acute Lymphoblastic Leukemia, Leukemia and other specialties. Johns Hopkins All Children's Hospital is involved with conducting 366 clinical trials across 530 conditions. There are 19 research doctors associated with this hospital, such as Stacie L. Stapleton, Jonathan Metts, MD, Jennifer B. Dean, and Peter H. Shaw.
Area of expertise
Cancer
Johns Hopkins All Children's Hospital has run 68 trials for Cancer. Some of their research focus areas include:
Brain Tumor
Johns Hopkins All Children's Hospital has run 54 trials for Brain Tumor. Some of their research focus areas include:
Top PIs
Stacie L. Stapleton
Johns Hopkins All Children's Hospital
8 years of reported clinical research
Jonathan Metts, MD
Johns Hopkins All Children's Hospital
5 years of reported clinical research
Jennifer B. Dean
Johns Hopkins All Children's Hospital
6 years of reported clinical research
Peter H. Shaw
Johns Hopkins All Children's Hospital
6 years of reported clinical research
Clinical Trials running at Johns Hopkins All Children's Hospital
Brain Tumor
Cancer
Acute Lymphoblastic Leukemia
Neuroblastoma
Leukemia
Testicular cancer
Burkitt Lymphoma
Brain Cancer
Rhabdomyosarcoma
Acute Myeloid Leukemia
Selumetinib vs. Chemotherapy
for Brain Cancer
This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting
2 awards
Phase 3
Chemotherapy + Radiation Therapy
for Brain Cancer
This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to diminish spinal cord relapses, 2) utilizing higher dose chemotherapy followed by conventional RT in patients who did not respond to induction chemotherapy. Chemotherapy drugs, such as carboplatin, etoposide, ifosfamide, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays or high-energy protons to kill tumor cells and shrink tumors. Studies have shown that patients with newly-diagnosed localized NGGCT, whose disease responds well to chemotherapy before receiving radiation therapy, are more likely to be free of the disease for a longer time than are patients for whom the chemotherapy does not efficiently eliminate or reduce the size of the tumor. The purpose of this study is to see how well the tumors respond to induction chemotherapy to decide what treatment to give next. Some patients will be given RT to the spine and a portion of the brain. Others will be given high dose chemotherapy and a stem cell transplant before RT to the whole brain and spine. Giving treatment based on the response to induction chemotherapy may lower the side effects of radiation in some patients and adjust the therapy to a more efficient one for other patients with localized NGGCT.
Recruiting
1 award
Phase 2
Lower Radiotherapy Dose
for Brain Tumors
This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.
Recruiting
1 award
Phase 2
10 criteria
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Frequently asked questions
What kind of research happens at Johns Hopkins All Children's Hospital?
Johns Hopkins All Children's Hospital is a medical facility located in Saint Petersburg, Florida. This center is recognized for care of Cancer, Brain Tumor, Soft Tissue Sarcoma, Acute Lymphoblastic Leukemia, Leukemia and other specialties. Johns Hopkins All Children's Hospital is involved with conducting 366 clinical trials across 530 conditions. There are 19 research doctors associated with this hospital, such as Stacie L. Stapleton, Jonathan Metts, MD, Jennifer B. Dean, and Peter H. Shaw.
Where is Johns Hopkins All Children's Hospital located?
Johns Hopkins All Children's Hospital is located at 501 6th Ave South, St. Petersburg, FL 33701. For directions, take the I-275 S to exit 22B for 5th Ave S towards Downtown St. Petersburg, turn left onto 5th Ave S, then right onto 6th St S, and the hospital will be on your right.
Who should I call to ask about financial aid or insurance network?
For financial assistance and insurance inquiries at Johns Hopkins All Children's Hospital, please use the following contact methods: - **Phone**: General billing and financial assistance - 1-855-662-3017. For cost-of-care estimates, including self-pay, call 727-767-7016. - **Email**: For financial assistance information, contact [billing@jhmi.edu](mailto:billing@jhmi.edu). - **Patient Itemized Bill Requests**: To obtain copies of service(s) performed, call 1-855-662-3017.
What insurance does Johns Hopkins All Children's Hospital accept?
Johns Hopkins All Children's Hospital accepts a variety of insurance plans, including commercial health plans (e.g., Aetna, Anthem Blue Cross Blue Shield of Virginia, CareFirst Blue Cross Blue Shield, Cigna Healthcare of the Mid Atlantic), military health system plans like Tricare Humana Military, Medicaid managed care/public health plans from District of Columbia, Maryland, and Virginia, and federal employee plans (e.g., Alliance Health Plan, American Postal Workers Plan, BlueCross/BlueShield Service Benefit Plan). It is crucial to contact the hospital directly to confirm coverage and referral requirements, as the acceptance of plans may change.
What awards or recognition has Johns Hopkins All Children's Hospital received?
Johns Hopkins All Children's Hospital, located in Saint Petersburg, Florida, is renowned for its exceptional pediatric care and research. It was named the best pediatric hospital in Florida for 2023-2024 by U.S. News & World Report and earned Magnet status for its nursing program from the American Nurses Credentialing Center (ANCC) Magnet Recognition Program®. The hospital is a key player in pediatric research, being part of the National Institutes of Health (NIH) consortium and the Institute for Advanced Clinical Trials (I-ACT) for Children, with its research and education facility serving as a hub for academic activities in neurosciences, cancer, cardiology, and neonatology.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.