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Johns Hopkins All Children's Hospital

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Saint Petersburg, Florida 33701
Global Leader in Cancer
Global Leader in Brain Tumor
Conducts research for Soft Tissue Sarcoma
Conducts research for Acute Lymphoblastic Leukemia
Conducts research for Leukemia
366 reported clinical trials
19 medical researchers
Photo of Johns Hopkins All Children's Hospital in Saint PetersburgPhoto of Johns Hopkins All Children's Hospital in Saint PetersburgPhoto of Johns Hopkins All Children's Hospital in Saint Petersburg

Summary

Johns Hopkins All Children's Hospital is a medical facility located in Saint Petersburg, Florida. This center is recognized for care of Cancer, Brain Tumor, Soft Tissue Sarcoma, Acute Lymphoblastic Leukemia, Leukemia and other specialties. Johns Hopkins All Children's Hospital is involved with conducting 366 clinical trials across 531 conditions. There are 19 research doctors associated with this hospital, such as Stacie L. Stapleton, Jonathan Metts, MD, Jennifer B. Dean, and Peter H. Shaw.

Area of expertise

1Cancer
Global Leader
Johns Hopkins All Children's Hospital has run 65 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage I
Stage II
2Brain Tumor
Global Leader
Johns Hopkins All Children's Hospital has run 57 trials for Brain Tumor. Some of their research focus areas include:
Stage IV
Stage I
Stage II

Top PIs

Clinical Trials running at Johns Hopkins All Children's Hospital

Brain Tumor
Acute Lymphoblastic Leukemia
Neuroblastoma
Leukemia
Cancer
Testicular cancer
Burkitt Lymphoma
Brain Cancer
Rhabdomyosarcoma
Acute Leukemia
Image of trial facility.

Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3
Image of trial facility.

Selinexor + Radiation

for Brain Cancer

This trial tests the safety and effectiveness of combining selinexor with radiation therapy in children and young adults with aggressive brain tumors. Selinexor is a drug that blocks a protein to stop cancer cells from growing. The study aims to find the best dose and see if this combination can shrink tumors.
Recruiting1 award Phase 1 & 21 criteria
Image of trial facility.

Chemotherapy + Radiation Therapy

for Brain Cancer

This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to diminish spinal cord relapses, 2) utilizing higher dose chemotherapy followed by conventional RT in patients who did not respond to induction chemotherapy. Chemotherapy drugs, such as carboplatin, etoposide, ifosfamide, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays or high-energy protons to kill tumor cells and shrink tumors. Studies have shown that patients with newly-diagnosed localized NGGCT, whose disease responds well to chemotherapy before receiving radiation therapy, are more likely to be free of the disease for a longer time than are patients for whom the chemotherapy does not efficiently eliminate or reduce the size of the tumor. The purpose of this study is to see how well the tumors respond to induction chemotherapy to decide what treatment to give next. Some patients will be given RT to the spine and a portion of the brain. Others will be given high dose chemotherapy and a stem cell transplant before RT to the whole brain and spine. Giving treatment based on the response to induction chemotherapy may lower the side effects of radiation in some patients and adjust the therapy to a more efficient one for other patients with localized NGGCT.
Recruiting1 award Phase 2

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Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security