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East Tennessee Childrens Hospital
Claim this profileKnoxville, Tennessee 37916
Global Leader in Leukemia
Global Leader in Tumors
Conducts research for Sarcoma
Conducts research for Brain Tumor
Conducts research for Lymphoma
211 reported clinical trials
2 medical researchers
Summary
East Tennessee Childrens Hospital is a medical facility located in Knoxville, Tennessee. This center is recognized for care of Leukemia, Tumors, Sarcoma, Brain Tumor, Lymphoma and other specialties. East Tennessee Childrens Hospital is involved with conducting 211 clinical trials across 345 conditions. There are 2 research doctors associated with this hospital, such as Susan E. Spiller and Ray C. Pais.Area of expertise
1Leukemia
Global LeaderStage II
Philadelphia chromosome positive
t(8;21)(q22;q22) positive
2Tumors
Global LeaderStage IV
Stage I
Stage II
Top PIs
Susan E. SpillerEast Tennessee Childrens Hospital6 years of reported clinical research
Expert in Tumors
Expert in Brain Tumor
45 reported clinical trials
98 drugs studied
Ray C. PaisEast Tennessee Childrens Hospital18 years of reported clinical research
Studies Leukemia
Studies Lymphoblastic Leukemia-Lymphoma
8 reported clinical trials
30 drugs studied
Clinical Trials running at East Tennessee Childrens Hospital
Rhabdomyosarcoma
Brain Tumor
Osteosarcoma
Acute Lymphoblastic Leukemia
Germ Cell Tumors
Non-Hodgkin's Lymphoma
Leukemia
Astrocytoma
Langerhans Cell Histiocytosis
Lymphoma
Combination Chemotherapy
for Rhabdomyosarcoma
This study is evaluating whether a combination of chemotherapy drugs is more effective than a single chemotherapy drug for treating rhabdomyosarcoma.
Recruiting2 awards Phase 35 criteria
Chemotherapy
for Rhabdomyosarcoma
Rhabdomyosarcoma is a type of cancer that occurs in the soft tissues in the body. This phase III trial aims to maintain excellent outcomes in patients with very low risk rhabdomyosarcoma (VLR-RMS) while decreasing the burden of therapy using treatment with 24 weeks of vincristine and dactinomycin (VA) and examines the use of centralized molecular risk stratification in the treatment of rhabdomyosarcoma. Another aim of the study it to find out how well patients with low risk rhabdomyosarcoma (LR-RMS) respond to standard chemotherapy when patients with VLR-RMS and patients who have rhabdomyosarcoma with DNA mutations get separate treatment. Finally, this study examines the effect of therapy intensification in patients who have RMS cancer with DNA mutations to see if their outcomes can be improved.
Recruiting2 awards Phase 3
Genetic Testing-Directed Therapy
for Pediatric Cancer
This study is evaluating whether genetic testing may help doctors plan better treatment for patients with solid tumors or non-Hodgkin lymphomas.
Recruiting1 award Phase 214 criteria
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Frequently asked questions
What kind of research happens at East Tennessee Childrens Hospital?
East Tennessee Childrens Hospital is a medical facility located in Knoxville, Tennessee. This center is recognized for care of Leukemia, Tumors, Sarcoma, Brain Tumor, Lymphoma and other specialties. East Tennessee Childrens Hospital is involved with conducting 211 clinical trials across 345 conditions. There are 2 research doctors associated with this hospital, such as Susan E. Spiller and Ray C. Pais.