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British Columbia Children's Hospital
Claim this profileVANCOUVER, British Columbia V6H 3V4
Global Leader in T-Lymphoblastic Leukemia/Lymphoma
Global Leader in Acute Lymphoblastic Leukemia
Conducts research for Lymphoid Leukemia
Conducts research for Leukemia
Conducts research for Uterine Tumors
331 reported clinical trials
21 medical researchers
Summary
British Columbia Children's Hospital is a medical facility located in VANCOUVER, British Columbia. This center is recognized for care of T-Lymphoblastic Leukemia/Lymphoma, Acute Lymphoblastic Leukemia, Lymphoid Leukemia, Leukemia, Uterine Tumors and other specialties. British Columbia Children's Hospital is involved with conducting 331 clinical trials across 631 conditions. There are 21 research doctors associated with this hospital, such as David B. Dix, Kevan Jacobson, Kathryn Selby, MD, and Kishore Mulpuri, FRCSC.Area of expertise
1T-Lymphoblastic Leukemia/Lymphoma
Global LeaderStage II
Stage IV
Stage III
2Acute Lymphoblastic Leukemia
Global LeaderStage II
Stage IV
Stage III
Top PIs
David B. DixBritish Columbia Children's Hospital5 years of reported clinical research
Studies T-Lymphoblastic Leukemia/Lymphoma
Studies Uterine Tumors
19 reported clinical trials
56 drugs studied
Kevan JacobsonBritish Columbia Children's Hospital3 years of reported clinical research
Studies Crohn's Disease
Studies Ulcerative Colitis
7 reported clinical trials
4 drugs studied
Kathryn Selby, MDBritish Columbia Children's Hospital8 years of reported clinical research
Studies Muscular Dystrophy
Studies Duchenne Muscular Dystrophy
4 reported clinical trials
7 drugs studied
Kishore Mulpuri, FRCSCBC Children's Hospital1 year of reported clinical research
Studies Midshaft Clavicle Fracture
Studies Hip dysplasia
4 reported clinical trials
7 drugs studied
Clinical Trials running at British Columbia Children's Hospital
Acute Myeloid Leukemia
Crohn's Disease
Testicular cancer
Colitis
Brain Tumor
Acute Lymphoblastic Leukemia
T-Lymphoblastic Leukemia/Lymphoma
Ovarian Tumors
Ovarian Choriocarcinoma
Ovarian Carcinoma
CPX-351 + Gilteritinib
for Acute Myeloid Leukemia
This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. CPX-351 is made up of daunorubicin and cytarabine and is made in a way that makes the drugs stay in the bone marrow longer and could be less likely to cause heart problems than traditional anthracycline drugs, a common class of chemotherapy drug. Some acute myeloid leukemia patients have an abnormality in the structure of a gene called FLT3. Genes are pieces of DNA (molecules that carry instructions for development, functioning, growth and reproduction) inside each cell that tell the cell what to do and when to grow and divide. FLT3 plays an important role in the normal making of blood cells. This gene can have permanent changes that cause it to function abnormally by making cancer cells grow. Gilteritinib may block the abnormal function of the FLT3 gene that makes cancer cells grow. The overall goals of this study are, 1) to compare the effects, good and/or bad, of CPX-351 with daunorubicin and cytarabine on people with newly diagnosed AML to find out which is better, 2) to study the effects, good and/or bad, of adding gilteritinib to AML therapy for patients with high amounts of FLT3/ITD or other FLT3 mutations and 3) to study changes in heart function during and after treatment for AML. Giving CPX-351 and/or gilteritinib with standard chemotherapy may work better in treating patients with acute myeloid leukemia compared to standard chemotherapy alone.
Recruiting2 awards Phase 3
Venetoclax + Chemotherapy
for Acute Myeloid Leukemia
This trial is testing whether adding venetoclax to standard chemotherapy can help young patients with relapsed AML. Venetoclax works by blocking a protein that helps cancer cells survive, making it easier for the chemotherapy to kill them. The study aims to find better treatment options for these patients who have limited choices. Venetoclax has been shown to improve overall survival in older and unfit patients with newly diagnosed acute myeloid leukemia when combined with lower intensity therapies.
Recruiting2 awards Phase 34 criteria
Diagnostic Testing
for Pediatric Leukemia
This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back after treatment or is difficult to treat may provide information about the patient's leukemia that is important when deciding how to best treat it, and may help doctors find better ways to diagnose and treat leukemia in children, adolescents, and young adults.
Recruiting1 award Phase 1 & 211 criteria
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Frequently asked questions
What kind of research happens at British Columbia Children's Hospital?
British Columbia Children's Hospital is a medical facility located in VANCOUVER, British Columbia. This center is recognized for care of T-Lymphoblastic Leukemia/Lymphoma, Acute Lymphoblastic Leukemia, Lymphoid Leukemia, Leukemia, Uterine Tumors and other specialties. British Columbia Children's Hospital is involved with conducting 331 clinical trials across 631 conditions. There are 21 research doctors associated with this hospital, such as David B. Dix, Kevan Jacobson, Kathryn Selby, MD, and Kishore Mulpuri, FRCSC.
Where is British Columbia Children's Hospital located?
**BC Children's Hospital Location and Access:**
- **Address:** 4480 Oak St, Vancouver, BC.
- **Entrances:** Use Entrance #42, #46, or #21.
- **Directions Inside:** Take the elevators to the third floor and follow the orange line.
Who should I call to ask about financial aid or insurance network?
For financial assistance and insurance-related inquiries at British Columbia Children's Hospital, contact the Medical Benefits program at 1-888-613-3232 (toll-free) or 250-387-9649 (Victoria). This program supports eligible children and teens with complex health needs by providing medical and bio-medical equipment, orthotics, splints, audiology supplies, medical supplies, extended therapies, dental/orthodontic and optical benefits, medical transportation, and Medical Services Plan coverage. The PharmaCare program offers coverage for prescription medications, orthotics, prosthetics, diabetic supplies, and blood glucose testing strips, while incontinence supplies funding is accessible through a Request for Medical Supplies Form or by calling 1-888-613-3232.
What insurance does British Columbia Children's Hospital accept?
BC Children's Hospital specializes in caring for the most seriously ill or injured children from across British Columbia. Families from outside Metro Vancouver with a child requiring care at BC Children's Hospital may be eligible for travel and accommodation support through the BC Family Residence Program. For detailed information about insurance plans accepted, please contact BC Children's Hospital directly or visit their website.
What awards or recognition has British Columbia Children's Hospital received?
British Columbia Children's Hospital Research Institute, located in Vancouver, British Columbia, is renowned for its groundbreaking research in child health, aiming to prevent, treat, and cure complex health conditions, developmental disorders, and chronic diseases originating in childhood. The institute boasts over 1,000 researchers and receives support from the BC Children's Hospital Foundation, Provincial Health Services Authority, and the University of British Columbia. Its funding priorities include research trainee awards for projects that directly improve the health of children and their families.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.