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Alfred I duPont Hospital for Children
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Wilmington, Delaware 19803
Global Leader in Cancer
Global Leader in Brain Tumor
Conducts research for Neuroblastoma
Conducts research for Acute Lymphoblastic Leukemia
Conducts research for Soft Tissue Sarcoma
381 reported clinical trials
16 medical researchers
Summary
Alfred I duPont Hospital for Children is a medical facility located in Wilmington, Delaware. This center is recognized for care of Cancer, Brain Tumor, Neuroblastoma, Acute Lymphoblastic Leukemia, Soft Tissue Sarcoma and other specialties. Alfred I duPont Hospital for Children is involved with conducting 381 clinical trials across 677 conditions. There are 16 research doctors associated with this hospital, such as Scott M. Bradfield, Ramamoorthy Nagasubramanian, Emi H. Caywood, and Michael Bober.
Area of expertise
Cancer
Alfred I duPont Hospital for Children has run 62 trials for Cancer. Some of their research focus areas include:
Brain Tumor
Alfred I duPont Hospital for Children has run 54 trials for Brain Tumor. Some of their research focus areas include:
Top PIs
Scott M. Bradfield
Alfred I duPont Hospital for Children
8 years of reported clinical research
Ramamoorthy Nagasubramanian
Nemours Children's Clinic-Jacksonville
5 years of reported clinical research
Emi H. Caywood
Alfred I duPont Hospital for Children
7 years of reported clinical research
Michael Bober
Nemours
12 years of reported clinical research
Clinical Trials running at Alfred I duPont Hospital for Children
Brain Tumor
Cancer
Testicular cancer
Burkitt Lymphoma
Leukemia
Wilms Tumor
Acute Lymphoblastic Leukemia
Neuroblastoma
Focal Segmental Glomerulosclerosis
Down Syndrome
Selumetinib vs. Chemotherapy
for Brain Cancer
This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting
2 awards
Phase 3
Chemotherapy + Radiation Therapy
for Brain Cancer
This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to diminish spinal cord relapses, 2) utilizing higher dose chemotherapy followed by conventional RT in patients who did not respond to induction chemotherapy. Chemotherapy drugs, such as carboplatin, etoposide, ifosfamide, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays or high-energy protons to kill tumor cells and shrink tumors. Studies have shown that patients with newly-diagnosed localized NGGCT, whose disease responds well to chemotherapy before receiving radiation therapy, are more likely to be free of the disease for a longer time than are patients for whom the chemotherapy does not efficiently eliminate or reduce the size of the tumor. The purpose of this study is to see how well the tumors respond to induction chemotherapy to decide what treatment to give next. Some patients will be given RT to the spine and a portion of the brain. Others will be given high dose chemotherapy and a stem cell transplant before RT to the whole brain and spine. Giving treatment based on the response to induction chemotherapy may lower the side effects of radiation in some patients and adjust the therapy to a more efficient one for other patients with localized NGGCT.
Recruiting
1 award
Phase 2
Health Information Collection
for Childhood Cancer
This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.
Recruiting
1 award
N/A
10 criteria
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Frequently asked questions
What kind of research happens at Alfred I duPont Hospital for Children?
Alfred I duPont Hospital for Children is a medical facility located in Wilmington, Delaware. This center is recognized for care of Cancer, Brain Tumor, Neuroblastoma, Acute Lymphoblastic Leukemia, Soft Tissue Sarcoma and other specialties. Alfred I duPont Hospital for Children is involved with conducting 381 clinical trials across 677 conditions. There are 16 research doctors associated with this hospital, such as Scott M. Bradfield, Ramamoorthy Nagasubramanian, Emi H. Caywood, and Michael Bober.
Where is Alfred I duPont Hospital for Children located?
**Directions to Alfred I duPont Hospital for Children:** - **From the North or South:** Take I-95 to Exit 8. Follow US 202 North to Route 141, then turn left onto Route 141. - **Address:** 1600 Rockland Road, Wilmington, DE 19803.
Who should I call to ask about financial aid or insurance network?
For financial assistance at Alfred I duPont Hospital for Children, families can apply through Nemours Children's Health Financial Assistance Program for reduced rates or no charge care for qualifying patients. Contact Nemours Financial Services or visit Nemours.org for application details and guidelines, where financial advocates are also available to assist. For insurance inquiries, reach out to the Patient Accounts department at Dupont Hospital.
What insurance does Alfred I duPont Hospital for Children accept?
The Alfred I duPont Hospital for Children accepts various insurance plans, including Highmark Blue Cross Blue Shield of Delaware and Highmark of Pennsylvania through the BlueCard program. Horizon Blue Cross Blue Shield of New Jersey terminated its hospital contract with Nemours/Alfred I duPont Hospital for Children in 2014, making it out of network for Horizon BCBSNJ members. Nemours Children's Health accepts many types of insurance plans; however, it's crucial to check with your insurance provider regarding coverage for specific services.
What awards or recognition has Alfred I duPont Hospital for Children received?
Alfred I. duPont Hospital for Children in Wilmington, Delaware, is renowned for its research and care in chronic and rare childhood diseases. Supported by the Nemours Foundation since 1936, it has achieved Magnet status multiple times and is consistently ranked by U.S. News & World Report’s Top Children’s Hospital awards. The hospital also offers biomedical research fellowship training and undergraduate summer scholarship programs for medical students.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.