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Advocate Children's Hospital-Oak Lawn
Claim this profileOak Lawn, Illinois 60453
Global Leader in Leukemia
Global Leader in Lymphoblastic Leukemia-Lymphoma
Conducts research for Lymphoid Leukemia
Conducts research for Acute Lymphoblastic Leukemia
Conducts research for Tumors
129 reported clinical trials
3 medical researchers
Summary
Advocate Children's Hospital-Oak Lawn is a medical facility located in Oak Lawn, Illinois. This center is recognized for care of Leukemia, Lymphoblastic Leukemia-Lymphoma, Lymphoid Leukemia, Acute Lymphoblastic Leukemia, Tumors and other specialties. Advocate Children's Hospital-Oak Lawn is involved with conducting 129 clinical trials across 306 conditions. There are 3 research doctors associated with this hospital, such as Sherjeel Sana, Corrie Fletcher, DO, and Alexander Javois, MD.Area of expertise
1Leukemia
Global LeaderStage II
BCR-ABL1 fusion positive
ABL-class fusion positive
2Lymphoblastic Leukemia-Lymphoma
Global LeaderStage II
BCR-ABL1 fusion positive
ABL-class fusion positive
Top PIs
Sherjeel SanaAurora Cancer Care-Southern Lakes VLCC5 years of reported clinical research
Studies Lymphoma
Studies Leukemia
4 reported clinical trials
15 drugs studied
Corrie Fletcher, DOAdvocate Children's Hospital Oak Lawn11 years of reported clinical research
Studies Asthma
1 reported clinical trial
2 drugs studied
Alexander Javois, MDAdvocate Children's Hospital3 years of reported clinical research
Studies Congenital Heart Defects
Studies Cardiovascular Disease
1 reported clinical trial
1 drug studied
Clinical Trials running at Advocate Children's Hospital-Oak Lawn
Acute Lymphoblastic Leukemia
Rhabdomyosarcoma
Leukemia
Ovarian Tumors
Lymphoma
Lymphoblastic Leukemia-Lymphoma
Alveolar Rhabdomyosarcoma
Ovarian Choriocarcinoma
Testicular Carcinoma
Ovarian Carcinoma
Levocarnitine
for Chemotherapy-Related Liver Protection in Leukemia and Lymphoma
This phase III trial compares the effect of adding levocarnitine to standard chemotherapy vs. standard chemotherapy alone in protecting the liver in patients with leukemia or lymphoma. Asparaginase is part of the standard of care chemotherapy for the treatment of acute lymphoblastic leukemia (ALL), lymphoblastic lymphoma (LL), and mixed phenotype acute leukemia (MPAL). However, in adolescent and young adults (AYA) ages 15-39 years, liver toxicity from asparaginase is common and often prevents delivery of planned chemotherapy, thereby potentially compromising outcomes. Some groups of people may also be at higher risk for liver damage due to the presence of fat in the liver even before starting chemotherapy. Patients who are of Japanese descent, Native Hawaiian, Hispanic or Latinx may be at greater risk for liver damage from chemotherapy for this reason. Carnitine is a naturally occurring nutrient that is part of a typical diet and is also made by the body. Carnitine is necessary for metabolism and its deficiency or absence is associated with liver and other organ damage. Levocarnitine is a drug used to provide extra carnitine. Laboratory and real-world usage of the dietary supplement levocarnitine suggests its potential to prevent or reduce liver toxicity from asparaginase. The overall goal of this study is to determine whether adding levocarnitine to standard of care chemotherapy will reduce the chance of developing severe liver damage from asparaginase chemotherapy in ALL, LL and/or MPAL patients.
Recruiting2 awards Phase 3
Imatinib + Chemotherapy
for Acute Lymphoblastic Leukemia
This study is evaluating whether a combination of drugs may help treat patients with a specific type of leukemia.
Recruiting2 awards Phase 3
Inotuzumab Ozogamicin
for Acute Lymphoblastic Leukemia
Recruiting2 awards Phase 3
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Frequently asked questions
What kind of research happens at Advocate Children's Hospital-Oak Lawn?
Advocate Children's Hospital-Oak Lawn is a medical facility located in Oak Lawn, Illinois. This center is recognized for care of Leukemia, Lymphoblastic Leukemia-Lymphoma, Lymphoid Leukemia, Acute Lymphoblastic Leukemia, Tumors and other specialties. Advocate Children's Hospital-Oak Lawn is involved with conducting 129 clinical trials across 306 conditions. There are 3 research doctors associated with this hospital, such as Sherjeel Sana, Corrie Fletcher, DO, and Alexander Javois, MD.