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Testicular Tissue Cryopreservation for Infertility (TTC Trial)

N/A

Recruiting

Led By Leslie Appiah, MD

Research Sponsored by University of Colorado, Denver

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Scheduled to undergo surgery, chemotherapy, drug treatment and/or radiation for the treatment or prevention of a medical condition or malignancy with risk of causing permanent and complete loss of subsequent testicular function

Timeline

Screening 3 weeks

Treatment Varies

Follow Up assessed at 6 months

Awards & highlights

TTC Trial Summary

This trial is looking at a new way to preserve fertility in male patients who may become infertile due to their disease or treatment. They want to see if freezing a piece of testicular tissue is

Who is the study for?

This trial is for male patients of any age who may become infertile due to a medical condition or treatments that are harmful to reproductive cells. It's specifically aimed at those for whom freezing testicular tissue is the only option to preserve fertility.Check my eligibility

What is being tested?

The study focuses on taking a small sample of testicular tissue and freezing it (cryopreservation) with the goal of preserving future fertility. The feasibility and acceptability of this procedure in patients at risk of infertility will be evaluated.See study design

What are the potential side effects?

Potential side effects might include discomfort, bruising, or infection at the biopsy site where tissue is taken from the testicles. Long-term effects are uncertain since this is an experimental procedure.

TTC Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am scheduled for treatment that may permanently affect my ability to produce sperm.

TTC Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ assessed at 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~assessed at 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and assessed at 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Feasibility, as Assessed via Percentage of Patients who Attempted a Procedure who were able to Cryopreserve

Feasibility, as Assessed via the Percentage of Eligible Patients who do a Procedure

Safety, as Assessed via the Number of Participants with At Least One Pre-specified

+1 more

Secondary outcome measures

Acceptability, as Assessed via Annual Survey Regret Score

TTC Trial Design

1Treatment groups

Experimental Treatment

Group I: Testicular Tissue CryopreservationExperimental Treatment1 Intervention

Enrolled participants will undergo a testicular tissue biopsy. The method and amount of tissue procurement will be at the discretion of the surgeon.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of Colorado, DenverLead Sponsor

1,746 Previous Clinical Trials

2,164,063 Total Patients Enrolled

11 Trials studying Infertility

30,323 Patients Enrolled for Infertility

Leslie Appiah, MDPrincipal InvestigatorUniversity of Colorado, Denver

2 Previous Clinical Trials

43,394 Total Patients Enrolled

1 Trials studying Infertility

26,704 Patients Enrolled for Infertility

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any available vacancies for patient participation in this clinical trial?

"Affirmative. Information on clinicaltrials.gov affirms the ongoing search for participants in this investigation. The trial was initially shared on September 28, 2020, and last revised on April 25, 2024. It aims to enlist a total of 60 patients from a single site."

Answered by AI

What is the current number of individuals who are being enrolled in this clinical investigation?

"Indeed, as per the details available on clinicaltrials.gov, it is evident that this ongoing medical investigation is actively seeking eligible individuals to participate. The trial was initially listed on September 28th, 2020, and its most recent update was made on April 25th, 2024. Specifically targeting recruitment of a total of 60 participants from a single designated site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Testicular Tissue Cryopreservation (TTC)

2020. "Testicular Tissue Cryopreservation (TTC)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06387498.

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