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Behavioural Intervention
Testing the Contribution of Orbitofrontal Cortex Networks to Decision-making in Healthy Subjects
N/A
Waitlist Available
Led By Christina Zelano, PhD
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 hour after intervention
Awards & highlights
Study Summary
This triallooks at how an area of the brain affects how we make decisions.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 1 hour after intervention
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 hour after intervention
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Behavior on devaluation task
Resting-state functional magnetic resonance imaging
Trial Design
2Treatment groups
Experimental Treatment
Group I: TMS targeting posterior OFC networksExperimental Treatment3 Interventions
Participants will receive TMS and sham targeting the posterior OFC network.
Group II: TMS targeting anterior OFC networksExperimental Treatment3 Interventions
Participants will receive TMS and sham targeting the anterior OFC network.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Real transcranial magnetic stimulation (TMS) before conditioning
2021
N/A
~90
Real transcranial magnetic stimulation (TMS) before devaluation test
2021
N/A
~90
Sham transcranial magnetic stimulation (TMS)
2021
N/A
~130
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Who is running the clinical trial?
Northwestern UniversityLead Sponsor
1,600 Previous Clinical Trials
920,111 Total Patients Enrolled
Christina Zelano, PhDPrincipal InvestigatorAssistant Professor
2 Previous Clinical Trials
88 Total Patients Enrolled
Thorsten Kahnt, PhDPrincipal InvestigatorAssociate Professor
3 Previous Clinical Trials
117 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You are taking medications that can increase the risk of seizures.You have a history of fainting or passing out.You have a history of eating disorders like anorexia nervosa, bulimia nervosa, or binge-eating disorder.You are currently on a diet or fasting.You have any metal implants in your body, such as surgical clips or joint pins.You have serious medical conditions like cancer, meningitis, chronic lung disease, or heart problems.You have had severe allergies in the past that required you to go to the hospital for treatment.You have had very severe asthma that required you to stay in the hospital for treatment.You are a regular smoker.You have difficulty hearing or experience ringing in your ears.You have a history of working with metal without wearing proper eye protection or have experienced injuries caused by metal fragments or small pieces.You have a fear of small, enclosed spaces.You have a history of significant mental health conditions like anxiety, depression, schizophrenia, or substance abuse.You have a higher risk of having seizures, such as a personal or family history of seizures, epilepsy, being pregnant, or having alcoholism.You have had a serious head injury that caused you to lose consciousness.You have had major neurological conditions in the past, such as epilepsy, dementia, multiple sclerosis, or brain tumors.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Research Study Groups:
This trial has the following groups:- Group 1: TMS targeting anterior OFC networks
- Group 2: TMS targeting posterior OFC networks
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there any available slots for participants in this trial?
"Affirmative. According to information hosted on clinicaltrials.gov, this medical trial is still recruiting participants after its initial posting date of July 18th 2022 and subsequent update from October 14th 2022. The research requires 60 subjects from a single center."
Answered by AI
How many subjects are engaged in this investigation?
"Affirmative, according to clinicaltrials.gov the trial was launched on July 18th 2022 and recently updated as of October 14th 2022, with a goal to enroll 60 patients from one dedicated medical centre."
Answered by AI
Does the research group accept minors for their trial?
"The parameters set for this study require that interested participants must be between 18 and 40 years of age. Conversely, there are 50 trials available for those under the age of majority and 371 specifically catered to individuals aged 65 or older."
Answered by AI
Are the qualifications for this research project compatible with my profile?
"This trial is seeking approximately 60 individuals between 18 and 40 years of age with healthy bodies. Participants must satisfy these criteria to be accepted into this clinical research project."
Answered by AI
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