← Back to Search

ReACT for Functional Seizures

N/A

Recruiting

Research Sponsored by University of Alabama at Birmingham

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Diagnosis of functional seizures

Males and females ages 11-18

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 5 to 7 months

Awards & highlights

Study Summary

This trial assesses the feasibility of recruitment, acceptability, retention, fidelity & adherence of two treatments for pediatric functional seizures.

Who is the study for?

This trial is for boys and girls aged 11-18 with a diagnosis of functional seizures. They must have internet access for telehealth sessions. Those with comorbid epilepsy, less than four seizures per month, severe intellectual disability, involvement in other therapies or severe mental illness are excluded.Check my eligibility

What is being tested?

The study compares two treatments: Retraining and Control Therapy (ReACT) and CATCH-IT to see which helps manage pediatric functional seizures better. Participants will be randomly assigned to one of the treatments at three different sites over an 18-month period.See study design

What are the potential side effects?

Since ReACT and CATCH-IT involve behavioral therapy rather than medication, traditional side effects like those seen with drugs are not expected. However, participants may experience emotional discomfort or stress during therapy.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have been diagnosed with functional seizures.

Select...

I am between 11 and 18 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 5 to 7 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~5 to 7 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 to 7 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Feasibility of Recruitment

Participant Adherence

Treatment Fidelity

Secondary outcome measures

Acceptability

Anxiety Sensitivity Index (ASI)

Beaver's Self-Report Family Inventory

+24 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: ReACT InterventionExperimental Treatment1 Intervention

During the initial visit participant will be randomized to either Retraining and Control Therapy (ReACT) or Competent Adulthood Transition with Cognitive Behavioral, Humanistic, and Interpersonal Training (CATCH-IT) intervention. ReACT includes 12 sessions with a therapist that will discuss a plan for managing FS. Participants will have 12 therapy sessions. The first session will be in-person which will last 2 hours and the subsequent 11 sessions will be conducted via video telehealth and each session will last 1 hour.

Group II: CATCH-IT InterventionActive Control1 Intervention

During the initial visit participant will be randomized to either Retraining and Control Therapy (ReACT) or Competent Adulthood Transition with Cognitive Behavioral, Humanistic, and Interpersonal Training (CATCH-IT) intervention. CATCH-IT involves the parent and child completing CBT modules on the web-based CATCH-IT platform, and they will meet with a CATCH-IT coach 12 times to discuss the modules and plan how to apply this to their life and their FS. Participants will have 12 therapy sessions. The first session will be in-person which will last 2 hours and the subsequent 11 sessions will be conducted via video telehealth and each session will last 1 hour.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

ReACT

2016

N/A

~100

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor

1,593 Previous Clinical Trials

2,282,528 Total Patients Enrolled

1 Trials studying Nonepileptic Seizures

224 Patients Enrolled for Nonepileptic Seizures

Yale UniversityOTHER

1,862 Previous Clinical Trials

2,742,460 Total Patients Enrolled

Baylor College of MedicineOTHER

1,002 Previous Clinical Trials

6,002,696 Total Patients Enrolled

Media Library

Nonepileptic Seizures Research Study Groups: ReACT Intervention, CATCH-IT Intervention

Nonepileptic Seizures Clinical Trial 2023: CATCH-IT Highlights & Side Effects. Trial Name: NCT05819268 — N/A

CATCH-IT 2023 Treatment Timeline for Medical Study. Trial Name: NCT05819268 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this exploratory research open to individuals 85 years and older?

"To qualify for this investigation, applicants must be between 11 and 18 years old. There are 44 trials designated to children under the age of 18 as well as 70 studies specifically allocated to persons over 65."

Answered by AI

How may I join this clinical research endeavor?

"Candidates for this clinical experiment should be aged 11 to 18 and must have been diagnosed with nonepileptic seizures. 108 individuals are required in order to complete the trial."

Answered by AI

Are there any remaining openings for participants in this trial?

"As detailed on clinicaltrials.gov, this medical study is no longer recruiting patients after being posted in May 1st 2023 and last updated April 5th 2023. Nevertheless, there are an abundance of alternative trials actively searching for participants at the moment."

Answered by AI

What is the primary goal of this research endeavor?

"The 5-7 month experiment is designed to assess Participant Retention. Secondary objectives include the Sense of Agency Scale, Quality of Life in Epilepsy for Adolescents (QOLIE-AD-48), and Treatment Preference Questionnaire which asks participants what treatment they prefer being randomized to."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures

Aaron Fobian 2024. "A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05819268.