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Motor Priming and Training for Post-Stroke Arm Weakness

N/A

Waitlist Available

Led By Daniel M Corcos, PhD

Research Sponsored by Northwestern University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

0-3 wrist flexion/wrist extension on Modified Ashworth Scale

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change in baseline fugl myer score at follow-up (8 weeks after treatment ends)

Awards & highlights

Study Summary

This trial is testing two different types of treatments to see which is more effective for people who have had a stroke. One treatment is motor priming, which is a warm-up for the brain that makes it better able to respond to treatment. The other is electrical stimulation priming, which uses low-intensity stimulation on the affected arm. The study team expects that the motor priming group will have more improvement.

Who is the study for?

This trial is for stroke survivors with severe arm weakness (hemiparesis) who had a stroke at least 6 months ago, without cerebellum involvement. They should have some wrist movement and score within a specific range on the FMUE TEST. Excluded are those with hearing issues, persistent headaches, certain orthopedic conditions, low cognitive scores, metal in head/neck area, seizure history, concussion with loss of consciousness, pacemakers/neurostimulators, pregnancy or metastatic cancer.Check my eligibility

What is being tested?

The study tests two treatments to improve arm function after stroke: one uses bilateral motor priming (BMP), where both wrists move together using a device; the other uses electrical stimulation priming (CP). Both groups receive task-specific training (TST). Participants will be randomly assigned to either group and undergo evaluations before treatment starts, after it ends and at an 8-week follow-up.See study design

What are the potential side effects?

While not explicitly mentioned in the provided information about this clinical trial's interventions – BMP + TST or CP + TST – potential side effects may include discomfort from wearing devices or fatigue due to exercise. The use of Transcranial Magnetic Stimulation for assessment could potentially cause mild headache or scalp sensations.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My wrist stiffness is mild to moderate.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change in baseline fugl myer score at follow-up (8 weeks after treatment ends)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change in baseline fugl myer score at follow-up (8 weeks after treatment ends)

This trial's timeline: 3 weeks for screening, Varies for treatment, and change in baseline fugl myer score at follow-up (8 weeks after treatment ends) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Fugl Myer Test of Upper Extremity Function

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Bilateral motor priming + Task specific training (BMP + TST)Experimental Treatment1 Intervention

A combination of bilateral motor priming (BMP) plus task specific training (TST) for 30 hours over 5 weeks.

Group II: Control Priming + TST (CP + TST)Active Control1 Intervention

The control priming is transcutaneous electric stimulation (TENS) set at a low threshold followed by the same task specific training protocol for 30 hours over 5 weeks.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of ChicagoOTHER

1,008 Previous Clinical Trials

822,170 Total Patients Enrolled

10 Trials studying Stroke

5,570 Patients Enrolled for Stroke

Shirley Ryan AbilityLabOTHER

195 Previous Clinical Trials

16,854 Total Patients Enrolled

70 Trials studying Stroke

8,265 Patients Enrolled for Stroke

University of Illinois at ChicagoOTHER

610 Previous Clinical Trials

1,559,379 Total Patients Enrolled

18 Trials studying Stroke

2,171 Patients Enrolled for Stroke

Media Library

Bilateral Motor Priming + Task Specific Training (BMP + TST) Clinical Trial Eligibility Overview. Trial Name: NCT03517657 — N/A

Stroke Research Study Groups: Bilateral motor priming + Task specific training (BMP + TST), Control Priming + TST (CP + TST)

Stroke Clinical Trial 2023: Bilateral Motor Priming + Task Specific Training (BMP + TST) Highlights & Side Effects. Trial Name: NCT03517657 — N/A

Bilateral Motor Priming + Task Specific Training (BMP + TST) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03517657 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies available for prospective participants in this experiment?

"The information posted on clinicaltrials.gov reveals that recruitment for this medical experiment is still ongoing, having first been advertised in January of 2018 and last updated in October 2021."

Answered by AI

How many participants are actively engaged in the experiment?

"Affirmative. Clinicaltrials.gov offers documentation that this medical trial, initially posted on January 20th 2018, is still recruiting participants. 76 individuals must be sourced from two distinct medical centres."

Answered by AI