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Study Summary
This trial studies how shockwave therapy can reduce knee pain and improve knee function in those with knee osteoarthritis who have subchondral bone marrow lesions.
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Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I've tried basic treatments like rest and pain relief for over 4 weeks without improvement.I haven't had treatments like PRP or bone marrow injections in my knee in the last 6 months.I have a systemic autoimmune disease like lupus or rheumatoid arthritis.I've had injections like PRP or stem cells in my bones or joints in the last 6 months.I am between 30 and 80 years old.My MRI shows bone marrow lesions in the knee's weight-bearing areas.My X-ray shows moderate to severe arthritis.I have had knee pain for over 2 months.My knee pain has been at least a 4 out of 10 in the past week.My pain is located in the same area as my bone marrow lesions.My pain and loss of function are not mainly due to bone marrow lesions.I am taking steroids for a condition other than cancer.I have not taken any IV bisphosphonate drugs in the last 2 years.I have had a steroid injection into a joint in the last 3 months.My pain is located in the same area as my bone marrow lesions.My X-Ray shows moderate to severe arthritis.My MRI shows bone marrow lesions in the knee's weight-bearing areas.
- Group 1: Control
- Group 2: Intervention
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are new participants still being accepted for this medical experiment?
"Clinicaltrials.gov has confirmed that this research is actively recruiting participants, since it was initially posted on October 13th 2022 and revised on the 24th of the same month."
Is geriatric recruitment being sought for this research endeavor?
"This clinical trial is seeking participants that are between the ages of 30 and 80. There are 39 studies for minors and 667 studies available to individuals over 65 years old."
May I partake in the experiment?
"This clinical trial seeks 30 individuals, aged between thirty and eighty years old, who currently experience knee pain. The prospective participants must be of both genders, possess a Kellgren-Lawrence (KL) score grade ranging from 2 to 4 that is detectable on X-Ray imaging technology, have a bone marrow lesion (BML) in the weight bearing region of their knee as seen by MRI scans, report experiencing discomfort for more than two months already and said pain should be localized within the same compartment which hosts BML(s). Furthermore, subjects would need to demonstrate at least four weeks worth of unsuccessful attempts at managing their symptoms through"
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