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SMART Interventions for Opioid Use Disorder
N/A
Waitlist Available
Research Sponsored by Karen Derefinko, PhD
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, an average of 8 months
Awards & highlights
Study Summary
This trial will compare the effectiveness of two different interventions for helping people stick to their medication-assisted treatment for substance abuse.
Who is the study for?
This trial is for adults with Opioid Use Disorder who are eligible to receive buprenorphine-naloxone medication, as determined by the study doctor. Participants must have access to a telephone and be able to understand spoken English.Check my eligibility
What is being tested?
The SMART Trial is testing two interventions aimed at improving adherence to medication-assisted treatment: Contingency Management (CM), which rewards patients for meeting certain goals, and a combination of Brief Motivational Interviewing + Substance Free Activities + Mindfulness (BSM).See study design
What are the potential side effects?
While specific side effects are not listed for the interventions being tested in this trial, common side effects associated with buprenorphine-naloxone include nausea, headache, dizziness, drowsiness, constipation, and sweating.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ through study completion, an average of 8 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, an average of 8 months
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Medication-Assisted Treatment (MAT) Adherence
Trial Design
3Treatment groups
Active Control
Group I: Contingency Management (CM)Active Control1 Intervention
CM is a behavioral method that employs external rewards for target behavior. Participants will receive gift cards for adhering to treatment (attending physician visits and being adherent to buprenorphine-naloxone) for their first 4 clinic visits.
Group II: Brief Motivational Interviewing + Substance Free Activities + Mindfulness (BSM)Active Control1 Intervention
Participants will receive the BSM intervention at 4 timepoints.
Group III: BSM+CMActive Control2 Interventions
BSM+CM is a combination of the two other arms. Participants may be randomized to this arm only in stage 2 of the SMART design.
Find a Location
Who is running the clinical trial?
Karen Derefinko, PhDLead Sponsor
3 Previous Clinical Trials
367 Total Patients Enrolled
University of MemphisOTHER
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11,609 Total Patients Enrolled
University of New MexicoOTHER
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3,528,509 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I am younger than 18 years old.The study doctor has approved me for buprenorphine-naloxone treatment.You have signs of being addicted to opioids.
Research Study Groups:
This trial has the following groups:- Group 1: Contingency Management (CM)
- Group 2: Brief Motivational Interviewing + Substance Free Activities + Mindfulness (BSM)
- Group 3: BSM+CM
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are researchers still enrolling people in this clinical trial?
"According to the latest information on clinicaltrials.gov, this trial is not currently looking for participants. This page was created on February 1st, 2022 and was last updated on April 13th, 2022. There are 547 other trials that are actively looking for patients."
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