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Stress Challenge for Myocardial Ischemia (MIMS3 Trial)

N/A
Waitlist Available
Led By Viola Vaccarino, MD, PhD
Research Sponsored by Emory University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age ≤60 at the time of MI
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 years
Awards & highlights

MIMS3 Trial Summary

This trial looks at how stress affects heart disease in men and women. It involves one clinic visit, a week of at-home monitoring, and follow-up phone calls every six months for three years.

Who is the study for?
This trial is for men and women aged 60 or younger who had a heart attack within the last 8 months. It's not suitable for those with recent severe heart issues, high blood pressure on test day, current use of certain psychotropic drugs (except antidepressants), pregnant or breastfeeding women, people over 360 pounds or with a BMI of 40+, and individuals with other serious health problems.Check my eligibility
What is being tested?
The study investigates how emotional stress affects heart disease in different genders. Participants will have one clinic visit, monitor their condition at home for a week, and receive follow-up calls every six months over three years to track their heart health under stress.See study design
What are the potential side effects?
Since this trial involves monitoring reactions to stress rather than medication, there are no direct side effects from drugs being tested. However, participants may experience stress-related symptoms during the study.

MIMS3 Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 60 years old or younger and have had a heart attack.

MIMS3 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cardiovascular Events
Secondary outcome measures
Cardiovascular Death
Cardiovascular Events Excluding Heart Failure
Myocardial Infarction or Cardiovascular Death
+1 more

MIMS3 Trial Design

1Treatment groups
Experimental Treatment
Group I: Young Participants with Prior MIExperimental Treatment1 Intervention
Participants aged 60 or less who experienced a MI within the last 8 months will undergo a stress challenge to assess MSI and will then be followed for 3 years.

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Who is running the clinical trial?

Emory UniversityLead Sponsor
1,645 Previous Clinical Trials
2,564,240 Total Patients Enrolled
National Heart, Lung, and Blood Institute (NHLBI)NIH
3,847 Previous Clinical Trials
47,817,926 Total Patients Enrolled
Viola Vaccarino, MD, PhDPrincipal InvestigatorEmory University

Media Library

Heart Attack Research Study Groups: Young Participants with Prior MI
Heart Attack Clinical Trial 2023: Young Participants with Prior MI Highlights & Side Effects. Trial Name: NCT04123197 — N/A
Young Participants with Prior MI 2023 Treatment Timeline for Medical Study. Trial Name: NCT04123197 — N/A
~0 spots leftby Jun 2024
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