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Cirrhosis With Gastric Antral Vascular Ectasia for Gastric Antral Vascular Ectasia (GAVE) (GAVE Trial)

N/A
Recruiting
Led By Xiao Jing Wang, MD
Research Sponsored by Mayo Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline
Awards & highlights

GAVE Trial Summary

The researchers are trying to find out more about Gastric Antral Vascular Ectasia (GAVE). This is a condition that affects the blood vessels in the stomach, leading to their enlargement and possible bleeding. It can also cause symptoms such as abdominal pain and nausea. By participating in this study, you will help us learn how often these symptoms occur and how they relate to stomach functioning.

Eligible Conditions
  • Gastric Antral Vascular Ectasia (GAVE)
  • Liver Cirrhosis

GAVE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Abridged Bowel Disease Questionnaire
Leuven Postprandial Distress Scale
Nepean Dyspepsia Index
Secondary outcome measures
Gastric Emptying Half Time (T 1/2) of Solids
Gastric Emptying Half Time (T 1/2) of liquids

GAVE Trial Design

2Treatment groups
Experimental Treatment
Group I: Cirrhosis Without Gastric Antral Vascular EctasiaExperimental Treatment1 Intervention
Patients without Gastric Antral Vascular Ectasia with cirrhosis will undergo gastric motor function testing. This will be measured by radioscintigraphy after overnight fast using a radiolabeled meal.
Group II: Cirrhosis With Gastric Antral Vascular EctasiaExperimental Treatment1 Intervention
Patients with Gastric Antral Vascular Ectasia with cirrhosis will undergo gastric motor function testing. This will be measured by radioscintigraphy after overnight fast using a radiolabeled meal.

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor
3,233 Previous Clinical Trials
3,771,802 Total Patients Enrolled
Xiao Jing Wang, MDPrincipal InvestigatorMayo Clinic

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias
Xiao Jing (Iris) Wang 2024. "Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06306963.
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~20 spots leftby Mar 2026
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