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Glutamate Imaging and Cognitive Testing for Depression
Study Summary
This trialstudies how glutamate affects depression and requires MRI/PET scans, cognitive testing, and 1-2 months of participation.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am between 18 and 65 years old.I haven't taken any medication for the last 2 weeks or only allowed medications for depression.I haven't taken any medication in the last 2 weeks or only allowed medications for PTSD.You must be able to speak English.I haven't taken any medication in the last 2 weeks or only allowed medications.I am currently experiencing a depressive episode.You cannot have any other medical conditions listed in the DSM-5 manual, except for those specifically required for this study.I have been diagnosed with PTSD according to DSM-5.I am currently experiencing a depressive episode.I have a bleeding disorder or am on blood thinners like Coumadin.I have been diagnosed with PTSD according to DSM-5 criteria.I am currently experiencing strong thoughts of harming myself.I am currently pregnant or breastfeeding.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
- Group 1: Cognitive Testing
- Group 2: Magnetic Resonance Imaging
- Group 3: Positron Emission Tomography
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Frequently Asked Questions
Are recruitment efforts underway for this research initiative?
"Confirmed, this trial is presently enrolling patients. The information was first published online on August 1st 2011 and the update occurred October 12th 2022, based off of clinicaltrials.gov."
May I join this particular experiment?
"This clinical trial is recruiting 180 individuals aged 18-65 with manic disorder who have not been diagnosed with any other DSM-5 conditions. Furthermore, each participant has to be unmedicated for at least two weeks or taking a permissible medication."
Are individuals aged 45 and older eligible to be participants in this experiment?
"This medical trial has a limited age range of 18 to 65. However, for those outside this demographic, there are 495 trials available for minors and 1573 studies open to seniors."
What is the aggregate number of participants in this research endeavor?
"Confirmed, the information on clinicaltrials.gov shows that this trial is actively seeking participants. The study was first posted on August 1st 2011 and updated most recently on October 12th 2022. 180 individuals are needed for enrollment at one medical centre."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
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