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Surgical Procedures for Reducing Ovarian Cancer Risk (SOROCk Trial)
SOROCk Trial Summary
This trial compares two surgical procedures for reducing the risk of ovarian cancer in women with BRCA1 mutations.
SOROCk Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSOROCk Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.SOROCk Trial Design
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Who is running the clinical trial?
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- I have chosen not to undergo or to delay surgery to remove my ovaries and fallopian tubes despite being at high risk due to BRCA1 mutation.I've had abnormal pelvic screening results in the last 6 months.I am between 35 and 50 years old.I am not healthy enough for my planned surgery.I am pregnant or planning to get pregnant using assisted methods and understand I can't get pregnant naturally after this.I am either before or after menopause.I have a confirmed BRCA1 mutation.I have at least one ovary and fallopian tube, or had a hysterectomy without removing both tubes.I have had ovarian, peritoneal, or fallopian tube cancer before.I am premenopausal or have hormone levels indicating I might be, despite having a hysterectomy.My ultrasound showed signs of ovarian cancer or complex cysts.I am having surgery to lower my risk of ovarian cancer due to BRCA1 mutation.I am a woman aged between 35 and 50.I have at least one ovary and fallopian tube, and haven't had both tubes removed.I have had cancer before and received chemotherapy in the last 30 days or radiation to my abdomen or pelvis at any time.
- Group 1: Group I (bilateral salpingectomy)
- Group 2: Group II (bilateral salpingo-oophorectomy)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What are the eligibility requirements for joining this research project?
"This trial is seeking a total of 2262 participants, all between 35 and 50 years old, that have been diagnosed with ovarian carcinoma."
Are any individuals being accepted for this testing protocol presently?
"Clinicaltrials.gov indicates that this trial is presently in the process of recruiting patients, having been first published on June 23rd 2020 and amended most recently on June 1st 2022."
Is this research project targeting participants below the age of seventy?
"Those hoping to be a part of this trial must fall within the 35-50 age bracket. Additionally, there are two other trials that accept participants below 18 years old and another 39 studies recruiting patients over 65."
How many participants are currently involved with this research endeavor?
"To make this research a success, 2262 participants that meet the criteria need to be recruited. Locations with available clinical trial sites include Baptist Health Floyd in New Albany, Indiana and Aurora Cancer Care-Racine in Racine, Wisconsin."
In how many distinct locations is this clinical experiment being conducted?
"This study is seeking to recruit 100 patients, with sites such as Aurora Cancer Care-Racine in Racine, Baptist Health Floyd in New Albany, and Carle Physician Group-Effingham in Effingham amongst other participating locations."
Who else is applying?
What state do they live in?
How old are they?
What portion of applicants met pre-screening criteria?
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