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Porcine vs Bovine Collagen Dressings for Wound Healing
N/A
Recruiting
Led By Amy C Killeen, DDS, MS
Research Sponsored by University of Nebraska
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, three months
Awards & highlights
Study Summary
This trial examines the effects of porcine and bovine collagen wound dressings on tooth extraction sites, measuring changes in soft tissue and bone density.
Who is the study for?
This trial is for adults aged 18-65 who need a front tooth or premolar extracted and grafted, are in good health overall, and don't smoke. They must be willing to consent to the study's procedures. People can't join if they've had radiation therapy or used bisphosphonates, are pregnant or breastfeeding, have conditions that affect bone healing, or can't make follow-up visits.Check my eligibility
What is being tested?
The study aims to see which works better for healing after a tooth is pulled: a wound dressing made from pig collagen (porcine membrane) versus one from cow collagen (bovine dressing). It will look at changes in soft tissue thickness and bone density at the site of the extraction.See study design
What are the potential side effects?
Possible side effects may include allergic reactions to either type of collagen dressing, irritation at the wound site, infection risk due to improper healing, and discomfort associated with any foreign material placed into an extraction site.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline, three months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, three months
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Soft tissue thickness in mm
Secondary outcome measures
Bone density in Hounsfield units
Interleukiin - 1beta, measured in pg/mL
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Porcine Collagen MembraneExperimental Treatment1 Intervention
Atraumatic tooth extraction with porcine collagen membrane placement
Group II: Bovine Collagen DressingActive Control1 Intervention
Atraumatic tooth extraction with bovine collagen dressing placement
Find a Location
Who is running the clinical trial?
University of NebraskaLead Sponsor
541 Previous Clinical Trials
1,144,729 Total Patients Enrolled
1 Trials studying Wound Healing
4 Patients Enrolled for Wound Healing
Amy C Killeen, DDS, MSPrincipal InvestigatorUniversity of Nebraska
3 Previous Clinical Trials
114 Total Patients Enrolled
1 Trials studying Wound Healing
4 Patients Enrolled for Wound Healing
Amy C Killeen, DDS,MSPrincipal InvestigatorUNMC College of Dentistry
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I am between 18 and 65 years old and do not smoke.I have had radiation therapy or used bisphosphonates.I cannot attend follow-up visits.I have a health condition that affects how my bones heal.I am in good overall health.I need a front tooth or premolar pulled and the area prepared for future dental work.
Research Study Groups:
This trial has the following groups:- Group 1: Bovine Collagen Dressing
- Group 2: Porcine Collagen Membrane
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is the geriatric population being incorporated into this clinical experiment?
"The eligibility guidelines for this clinical trial specify that participants must be 18 years or older and no more than 65."
Answered by AI
What are the eligibility requirements for participating in this clinical investigation?
"In order to be eligible, applicants must have wound healing and fall in the 18-65 age range. 24 persons will be accepted into this clinical trial in total."
Answered by AI
What potential risks are associated with Porcine Collagen Membrane usage?
"Porcine Collagen Membrane has been approved as a viable medical intervention, resulting in it receiving the highest score of 3."
Answered by AI
Is the enrollment process for this trial still open?
"This research endeavour, which was first posted on May 1st 2023 and last amended 4/5/2023, is currently not in need of participants. However, there are 782 other clinical trials actively searching for enrollees at the present moment."
Answered by AI
Who else is applying?
What site did they apply to?
University of Nebraska Medical Center, College of Dentistry
What portion of applicants met pre-screening criteria?
Met criteria
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