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Sertraline for PTSD (SSRI Trial)
SSRI Trial Summary
This trial is testing a brief screening to see if it can predict which people with PTSD or depression will respond well to SSRI medications. 94 people are needed for the 17 week study.
SSRI Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSSRI Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.SSRI Trial Design
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Who is running the clinical trial?
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- I do not have any severe liver, kidney, or other unstable health conditions.I have significant issues with my nervous system.I have a history of bipolar I, schizophrenia, or another psychotic disorder.I have tried sertraline before and it didn't work for me.I am interested in trying an SSRI medication.You have a serious problem with drugs or alcohol.You are currently at risk of harming yourself or others.You are allergic or have a bad reaction to sertraline.I haven't taken drugs for serotonin issues in the last 3 months.You are currently participating in therapy specifically focused on trauma.I do not have a severe brain injury or any condition faking illness.A psychiatrist agrees SSRIs are suitable for my mental health issues.I have been on a stable dose of psychiatric medication for 3 months.You have experienced a traumatic event that meets the criteria for PTSD according to the DSM-5.I have been diagnosed with PTSD, subthreshold PTSD, or major depression.
- Group 1: Placebo only arm
- Group 2: Sertraline arm
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
To what degree does the Sertraline arm of this research present a hazard to individuals?
"There is existing approval for Sertraline, making it a safe option and receiving a score of 3."
What is the maximum number of participants for this research project?
"Indeed, clinicaltrials.gov reports that this research is still looking for participants. This study was introduced on September 11th 2019 and has most recently been updated on March 9th 2022; 94 individuals will be recruited from one single location."
What qualifications must a person possess to partake in this clinical research?
"To qualify for this clinical trial, applicants must have a documented case of post traumatic stress disorder and be between the ages of 18-70. Currently, a total of 94 patients are being sought after."
What mental health issues is Sertraline arm frequently prescribed for?
"Sertraline arm is often employed to treat premenstrual dysphoric disorder and can prove useful in treating anxiety disorders, binge eating disorder (BED), and obsessive-compulsive disorder."
Does this clinical trial extend to elderly adults, aged 65 or above?
"The trial is open to any individuals aged 18 or over and under the age of 70."
Is registration still open for this research trial?
"This clinical trial is presently recruiting, as reported on the clinicaltrials.gov website. The initial post date was September 11th 2019 and it has been updated most recently on March 9th 2022."
Who else is applying?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
What questions have other patients asked about this trial?
How responsive is this trial?
Typically responds via
Most responsive sites:
- VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA: < 48 hours
Average response time
- < 2 Days
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