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Anti-Inflammatory Lipid Mediator for Asthma (ALMA; LIMA Trial)
ALMA; LIMA Trial Summary
This trial will study whether a synthetic nitro-fatty acid (CXA-10) can help suppress the systemic and airway inflammation that contributes to the obese asthmatic phenotype.
ALMA; LIMA Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowALMA; LIMA Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.ALMA; LIMA Trial Design
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Who is running the clinical trial?
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- I am between 18 and 65 years old.I was hospitalized for asthma in the last 6 weeks.I have not taken any corticosteroids in the last 4 weeks.I have not had a respiratory infection in the last 4 weeks.You have a body mass index (BMI) of 30 or higher.I have been diagnosed with asthma for over 6 months and respond to asthma medication.I visited the ER for asthma in the last 4 weeks.I've been on stable asthma medication for at least 4 weeks.I am a woman who cannot become pregnant or will use birth control during the study.I have had 3 or more severe asthma attacks in the last year.I am currently smoking or quit less than a year ago.
- Group 1: CXA-10
- Group 2: Matching Placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Can elderly citizens participate in this clinical trial?
"The age range for participants in this study is 18 to 65 years old."
Is CXA-10 a new medication or has it been studied before?
"CXA-10 is being studied in 1 active clinical trial, with none of the investigations currently in Phase 3. Some of the research for CXA-10 is based in Aurora, Colorado; however, there is at least one other location where similar studies are taking place."
Could I potentially enroll in this research program?
"60 individuals will be accepted into this trial that aim to study the effects of the medication on obesity. To qualify, participants must fall within the 18 to 65 age range and currently suffer from obesity."
How many people are being asked to participate in this research?
"Presently, this study is not enrolling patients. The listing for this clinical trial was first posted on September 10th, 2019 and updated most recently on July 11th, 2022. However, if you are still seeking treatment options, there are 1,313 other trials actively recruiting patients with obesity and one CXA-10 trial currently looking for participants."
Are people still being recruited for participation in this clinical trial?
"This research is not currently looking for more participants as it was last updated on 7/11/2022. The study, which began recruitment on 9/10/2019, has since finished. Although this trial is no longer active, there are 1,314 other trials that patients can consider enrolling in."
Has CXA-10 undergone FDA approval for general use?
"CXA-10 falls into the Phase 2 category, meaning that while there is evidence suggesting it is safe, there is no data currently indicating that it is an effective treatment. Our analysts gave it a score of 2."
Who else is applying?
What state do they live in?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
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