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Second Look Laparoscopy (SLL) for Ovarian Cancer

Phase 2

Recruiting

Led By Rachel Grisham, MD

Research Sponsored by Memorial Sloan Kettering Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patients assigned female at birth≥ 18 years of age

Suspected or known stage III-IV epithelial ovarian cancer for which the patient has undergone, or is planned to undergo, attempted primary or interval debulking surgery

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 12 weeks

Awards & highlights

Study Summary

This trial is looking at the health outcomes of people with advanced ovarian cancer who undergo a second look laparoscopy (SLL) after their first round of chemotherapy. They are comparing the outcomes of

Who is the study for?

This trial is for individuals with advanced ovarian cancer who have finished their first round of chemotherapy. It aims to see if a procedure called Second Look Laparoscopy (SLL) can help determine the presence of minimal residual disease—tiny amounts of cancer cells left after treatment.Check my eligibility

What is being tested?

The study tests the effectiveness and safety of Second Look Laparoscopy (SLL) in detecting minimal residual disease in patients post-chemotherapy. Researchers will compare health outcomes between those with MRD and without MRD at the time of SLL.See study design

What are the potential side effects?

While specific side effects are not listed, typical risks associated with laparoscopic procedures may include infection, bleeding, pain at incision sites, and potential complications from anesthesia.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am 18 or older and was assigned female at birth.

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I have advanced ovarian cancer and am undergoing or planning to undergo surgery to remove as much of it as possible.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

minimal residual disease (MRD) status

Trial Design

1Treatment groups

Experimental Treatment

Group I: Second Look Laparoscopy (SLL)Experimental Treatment1 Intervention

Patients will be treated with standard of care observation or maintenance therapy as per investigator decision.The only investigational intervention performed through this study is the SLL.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Memorial Sloan Kettering Cancer CenterLead Sponsor

1,937 Previous Clinical Trials

588,240 Total Patients Enrolled

72 Trials studying Ovarian Cancer

42,893 Patients Enrolled for Ovarian Cancer

Rachel Grisham, MDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center

6 Previous Clinical Trials

628 Total Patients Enrolled

1 Trials studying Ovarian Cancer

225 Patients Enrolled for Ovarian Cancer

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are multiple facilities within the city conducting this study?

"At present, this investigation is taking place at 9 distinct centers. These sites are situated in Basking Ridge, Montvale, Boston, and several other locations. Opting for the nearest site would reduce travel obligations when joining the study."

Answered by AI

Are there any ongoing efforts to enroll participants for this particular trial?

"As per clinicaltrials.gov, this research endeavor is presently in search of suitable participants. The trial was initially listed on 1/26/2024 and last revised on the same date."

Answered by AI

Are there any potential risks associated with the medical procedure known as Second Look Laparoscopy (SLL) for individuals?

"Based on our evaluation at Power, the safety rating for Second Look Laparoscopy (SLL) is 2 as this trial falls under Phase 2. Safety data exists but efficacy evidence is lacking."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Study of Second Look Laparoscopy (SLL) in People With Ovarian Cancer Who Have Completed Their First Course of Chemotherapy

2024. "A Study of Second Look Laparoscopy (SLL) in People With Ovarian Cancer Who Have Completed Their First Course of Chemotherapy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06240598.

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