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Reduced-Dose Radiotherapy for Head and Neck Cancer (HN001 Trial)
HN001 Trial Summary
This trial will test if a lower dose of radiation is just as safe and effective for treating head and neck cancer.
HN001 Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.HN001 Trial Design
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Who is running the clinical trial?
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- I am planning to undergo radiotherapy as my main or additional cancer treatment.I am able to get out of my bed or chair and move around.My cancer has spread to distant parts of my body.I do not have conditions like ataxia telangiectasia or scleroderma that prevent head and neck radiation.I am 18 years old or older.I have been diagnosed with squamous cell carcinoma in the throat.I have early-stage cancer and may not need chemotherapy.I agree to use birth control during and for 6 months after my radiation treatment.I need chemotherapy to join because my cancer is advanced or has spread to lymph nodes.I am currently receiving treatment for oropharyngeal cancer.My cancer is HPV-positive as confirmed by specific tests.My cancer is advanced but I'm not planning to have chemotherapy with other treatments.I had surgery for throat cancer less than 8 months ago.I have been cancer-free for at least 3 years, except for non-melanoma skin cancer.I have had radiation therapy to my head or neck before.
- Group 1: Reduce Dose without Concurrent Chemotherapy Non- Rapid Responder
- Group 2: Reduce Dose with Concurrent Chemotherapy Non-Rapid Responder
- Group 3: Reduce Dose without Concurrent Chemotherapy Rapid Responder
- Group 4: Reduce Dose with Concurrent Chemotherapy Rapid Responder
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many different sites are currently managing this trial?
"This clinical trial is currently enrolling from 4 different sites, which are located in Charlottesville, Norfolk and Richmond as well as other locales. It may be beneficial to select the closest site in order to minimize transport needs should you choose to participate."
Is enrollment still taking place for this clinical trial?
"Per the information found on clinicaltrials.gov, this particular trial is no longer enrolling patients. It was initially posted in September of 2023 and updated as recently as July 22nd of that same year; yet despite its recent activity, 2647 other medical trials are actively searching for applicants right now."
What safety considerations should be taken into account when administering Reduced Dose without Concurrent Chemotherapy Non- Rapid Responder to patients?
"Based on our internal assessment, the safety of Reduce Dose without Concurrent Chemotherapy Non- Rapid Responder has been rated a 2. This is due to there being existing data that suggest its security but none indicating efficacy."
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