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SCFA Supplementation for Radiation Poisoning
Study Summary
This trial is testing whether a common, safe, and low-cost therapy can help reduce gastrointestinal toxicity from radiation therapy.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have a confirmed GI, urologic, or gynecologic cancer and will receive radiation of at least 40Gy to my abdomen or pelvis.I am not taking any medications or treatments that are not allowed in this study.I am currently taking vorinostat.I have had radiation therapy to my abdomen or pelvis.I finished my last cancer treatment 14 days ago and have recovered from its side effects.My kidney function is reduced with a creatinine clearance below 50 mL/min.I am a man who will use birth control during and after the study if my partner can have children.I am a woman who can have children and have a recent negative pregnancy test.I have moderate to severe diarrhea not caused by laxatives.I have active cancer spread to my brain or spinal cord.I am 18 years old or older.I can take care of myself but might not be able to do heavy physical work.I have had chemotherapy or surgery before.I am currently on medication for an infection.You have a severe allergy to nuts.I have a history of inflammatory bowel disease or problems with my digestive system's movement.I have been diagnosed with congestive heart failure.
- Group 1: Placebo (Tapioca)
- Group 2: Short Chain Fatty Acid (SCFA)
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there other ongoing investigations related to Short Chain Fatty Acid (SCFA)?
"There are currently 6 ongoing trials studying the efficacy of Short Chain Fatty Acid (SCFA). 2 of these trials have progressed to Phase 3. The majority of research locations for SCFA are in Chapel Hill, North carolina; although, there are a total 12 sites running clinical trials for this medication."
Are new patients being enrolled in this research project at this time?
"No, this particular clinical trial is not currently looking for new participants. This is based on the information available on clinicaltrials.gov which shows that the last update to this study was made on 11/11/2022. That said, there are 50 other trials happening right now that are accepting patients."
To date, how many people have signed up for this clinical research?
"Unfortunately, this particular study is no longer recruiting volunteers. The trial was originally posted on 1/1/2023 but the most recent update was 11/11/2022. There are currently 44 other studies that deal with radiation toxicity and 6 for Short Chain Fatty Acid (SCFA) actively looking for patients if you are interested in participating in a clinical trial."
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